Unvailed adrenal insufficency after starting Thyroid.

[hardasnails1973]

@MetalMX 2171 wrote:

My 24hour urine aldosterone came back undetectable. Range 17-69.

Comment was: aldosterone level was undetectable or too low.

When i did my cortisol and ACTH last time both we’re elevated but i forgot to take my thyroid medication that day.

I am not sure on bloods i think even a person with addisons could draw elevated cortisol due to stress from drawing the blood which is bullshit.

Im in adrenal madness having dizziness, nausea, high pulse if i dont take in salt with water, exhaustion and so forth.

I had to go to the ER 3 times this week due to symptoms. But blood pressure was normal. Pulse was bradycardic at times.

Only think i see on bloodwork is consistently elevated liver enzymes. Which could be due to the adrenal insufficiency itself, and Low normal WBC Count which would also point to adrenal problem.

i would look to rule out hepattis since enzyme are elevated which could be due to low thyroid or magnesium deficeincy due to low aldosterone.

[pmgamer18]

My levels were very low only thing that helps me is .1mgs of Florinef one needs to work up to this dose and it is = to 10 mgs of HC. or Cortef. I need to add about a 1/2 tsp of good Sea Salt to my water 3x’s at day I am also on 30 mgs of cortef HC a day. Read this link.
http://livingnetwork.co.za/hormones/adrenal-fatigue/
And in this link they talk about low Aldosterone levels and dumping your sodium.
http://www.tuberose.com/Adrenal_Glands.html
I am Secondary meaning my Pituitary dose not tell my body to make hormones so I have to treat them all. I will even be starting on Growth Hormone when it get approved at my Drug care plain.
@MetalMX 2171 wrote:

My 24hour urine aldosterone came back undetectable. Range 17-69.

Comment was: aldosterone level was undetectable or too low.

When i did my cortisol and ACTH last time both we’re elevated but i forgot to take my thyroid medication that day.

I am not sure on bloods i think even a person with addisons could draw elevated cortisol due to stress from drawing the blood which is bullshit.

Im in adrenal madness having dizziness, nausea, high pulse if i dont take in salt with water, exhaustion and so forth.

I had to go to the ER 3 times this week due to symptoms. But blood pressure was normal. Pulse was bradycardic at times.

Only think i see on bloodwork is consistently elevated liver enzymes. Which could be due to the adrenal insufficiency itself, and Low normal WBC Count which would also point to adrenal problem.

[MetalMX]

@hardasnails1973 2173 wrote:

i would look to rule out hepattis since enzyme are elevated which could be due to low thyroid or magnesium deficeincy due to low aldosterone.

I will definitely have this tested also. Their has been so much blood work done in the past year i have a whole folder without enough answers.

My SHBG is also very high (11-75) 85 and last one 109.

But this could also be due to low cortisol, because i haven’t been “challenged” with enough thyroid while doing bloodwork or saliva testing.

When increasing thyroid doses i experience air hunger, weakness and similar symptoms and when i tried T3 after a few days i experienced severe symptoms pointing to adrenals especially palpitations.

When trying Florinef 25mcg. I experienced high blood pressure 150/100, high pulse, and generalised weakness for the next day + dizziness etc… This was a few days ago, this tells me i don’t need it.

HAN have you seen elevated liver enzymes in people with adrenal insufficiency/ hidden low cortisol?

If cortisol is low, HC will also improve aldosterone shouldn’t it? Or would Isocort improve Aldosterone levels moreso?

Thank you for your reply mate ;).

[MetalMX]

Sorry forgot to mention my liver enzymes we’re normal in the previous blood test.

When i started Plain T3 40-50mcg per day after 5-7 days i began having these adrenal symptoms and wound up in the ER. Then my liver enzymes we’re elevated.

[MetalMX]

With average temperatures of 95.9F i certainly cannot be in a healthy metabolic state.

I haven’t checked Reverse T3 bloods just yet, will with the next blood draw.

I’ve made up my own list. I haven’t checked my lipids since last year and thats when they we’re all low out of range.

Am doing morning 8am:

Cortisol
ACTH
Renin
TSH
Free T3
Free T4
Reverse T3
Lipid Profile
Homocysteine
Insulin

I am on 120mg dessicated thyroid extract and am now switching to ERFA Thyroid. If i can get my adrenals working right then T3 would work best for me i think and not cause any symptoms i think the symptoms with T3 i experienced we’re just due to adrenals. Then this would lower RT3 and get my metabolism going and low body temp up. Because i didn’t have that many problems with T3 for the first few days just marked improvements only after a few days i began experiencing severe symptoms.

[hardasnails1973]

hypothyroid
magnesium deficency
antifungals
starvation
liver malfucntion
high cortisol can all cause elevated liver enzymes

thyroid will drive up SHBG big time (synthetic that is) This is why i like to use efra because it can be absorbed like old armour under the tongue and worked great for people like you and me have horrible digestion problems due to hiddden infections with in side the digestion tract.

For us metal here is how i see it
1) identifiy hidden infections in the digestion tract or heavy metals from tattoss that have red ink in them
2) remove them with appropiate measures
3) Supporting methylation will help, but clearing the gut will restore methylation
4) Hormone support accordingly (thyroid and adrenals)
5) Back fill with properl nutrition

From dealing with many cases who do not respond to thyroid meds and adrneals there is a immune response that needs to be dealt with first because if you stimulate the immune system and body is not prepared to deal with it then it will cause a back log.

People first line of defense against a tissue immune response is cholesterol .. people with low cholesterol have immune system imbalance, hidden low grade infection (herpes, dybiosis, my case staphy infection in intestinal tract that has not gotten rid of yet, celiac)

[MetalMX]

@hardasnails1973 2200 wrote:

hypothyroid
magnesium deficency
antifungals
starvation
liver malfucntion
high cortisol can all cause elevated liver enzymes

thyroid will drive up SHBG big time (synthetic that is) This is why i like to use efra because it can be absorbed like old armour under the tongue and worked great for people like you and me have horrible digestion problems due to hiddden infections with in side the digestion tract.

For us metal here is how i see it
1) identifiy hidden infections in the digestion tract or heavy metals from tattoss that have red ink in them
2) remove them with appropiate measures
3) Supporting methylation will help, but clearing the gut will restore methylation
4) Hormone support accordingly (thyroid and adrenals)
5) Back fill with properl nutrition

From dealing with many cases who do not respond to thyroid meds and adrneals there is a immune response that needs to be dealt with first because if you stimulate the immune system and body is not prepared to deal with it then it will cause a back log.

People first line of defense against a tissue immune response is cholesterol .. people with low cholesterol have immune system imbalance, hidden low grade infection (herpes, dybiosis, my case staphy infection in intestinal tract that has not gotten rid of yet, celiac)

I have finally switched to thyroxine and cytomel. 75mg thyroxine, 20mcg cytomel and am today feeling better. It may be i was just not responding to the natural thyroid and all the chronic hypothyroid symptoms we’re killing me. Today i feel much better than i have for weeks.

I will definitely stay with these synthetic meds for now. I will try ERFA thyroid but am not sure how it will work for me, i guess their is only one way to find out.

My body is likely in starvation mode due to low thyroid for so so long. And i dont have any appetite during the day it mostly comes more at night and i actually wake up hungry 2 maybe 3 times per night and eat then, very odd but this is what my body is just doing i cannot get out of this schedule. This is disrupting my REM sleep and hormonal release also which i know isn’t good.

I have been supporting my body to the best of my ability nutritionally with solid nutrition. I use a high dose of lactate free probiotics from custom probiotics 250billion cfu per teaspoon per day. EVCO oil, hemp seed oil, milled flaxseeds, avocados and things such as those for fats. I also constantly use digestive enzymes as well as oxbile with whatever i eat. I have excess acid production at times and don’t need Betaine HCL i have found. I have used glutamine also with success.

I use a comprehensive multi-vitamin/mineral from kirkman labs. And methylation support folinic acid, Methylcobalamin, P5P with magnesium glycinate and added magnesium amino acid chelate 500mg per day.

Doing all this i doubt i will have any hidden infections, but my digestion is still poor obviously from low thyroid for so long. And i definitly feel i have liver dysfunction issues. I have allergies and shortness of breath for no reason to certain things. My IgE is 4000 while it should be (<100). I cannot drink coffee or i feel i will pass out the same goes for even a bit of alcohol and i start feeling unwell.

I have no more candida issues for a while now this has been eliminated. I also avoid wheat, gluten and dairy.

I have been chelating mercury with the product you recommended for me and it has worked very well and a lot of my peripheral neuropathy like symptoms we’re eliminated with the supplement you recommended which i thank you for.

As i said low body temperatures with constant fluctuation of 35.5, 36.0, 35.0C. Low cholesterol would also be very possible which i need to check because i do crave fats just by themselves.

My mother has these same issues as i, yet she has no hashimoto’s. She has constantly fluctuating body temperatures and a fatty liver of unknown cause with elevated liver enzymes slightly like mine.

If you have any secrets to clearing the gut please share if you think their is more i could do with this… The only infection which i can think of that i could have is sinusitits since i have difficulty smelling things as well as pressure between my eyes and runny and full nose at times. Also have had issues with difficulty urinating and bladder functions for months on and off.

This is the product which i have tried before and which i still have at my home which i could try to use again it worked well the first time.

Intestaclear:

http://www.allnaturaladvantage.com.au/Products/intestaclear.htm

I had a pinworm infestation which i have now cleared.

Cholesterol pills might be just what i need, those sonic cholesterol ones you recommended i will look into once i get bloods back.

[MetalMX]

HAN I have not tried HC yet so i have not being treating adrenals whatsoever while on thyroid meds. No wonder i am getting all these adrenal symptoms.

But mostly the symptoms are no energy and exhaustion, muscle weakness, dizziness/light-headedness, weight loss im 174-178lbslbs at 6″4 now, frequent thirst, fluid retention in my legs, inability to grow much facial hair at all, persistent low body temperature, no motivation, no to low appetite during the day – feels like i cant digest food, stomach tingling and tingling sensations in the arms and calves.

It is not like these are constant symptoms once i started thyroid meds maybe 1-2 days i’m good then i crash and all these symptoms arise. I have motivation for everything for 1-2 days then no motivation or energy lol… god damn adrenals!!!!!!!!!!

[MetalMX]

I just found out i have Pyroluria positive via urine Kryptopyrolles this would itself cause many symptoms.

Urinary Pyrrole Analysis Results:

– 28.1 (ug/dL) – Positive

Critical Values:

HPL < 10ug/dL = Normal
10ug/dL – 15ug/dL = Borderline
HPL > 15ug/dL = Elevated

What dosages should i begin of Zinc, P5P and manganese for this disorder HAN?

Also i have recently begin having what seems like kidney issues which i’m seeing a specialist about in a days time. Dizziness, nausea, aching in my flank, shortness of breath, difficulty peeing and swelling in my legs and face. Can this be due to pyroluria?

What i was suspecting was adrenal issues but maybe these are actual kidney issues its hard to distinguish since the symptoms are quite similar. The only way for me to know is once i see the nephrologist to rule out any kidney disorders and do the above blood test for thyroid/adrenals/cholesterol etc…

The journey never ends… 🙁

[MetalMX]

My CBC is as follows:

Haemoglobin – 152 g/L (130 – 180)
White Cell Count – 4.2 x10^9/L (3.7 – 9.5)
Platelets – 183 x10^9/L (150 – 400)
Red Cell Count – 5.2 x10^12/L (4.3 – 5.7)
Haemocrit – 0.45 (0.40 – 0.54)
MCV – 86 fL (82 – 98)
MCH – 29 pg (27 – 32)
MCHC – 339 g/L (300 – 350)

Absolute Neutrophils – 2.2 x10^9/L (2.0 – 8.0)
Absolute Lymphocytes – 1.5 x10^9/L (1.0 – 4.0)
Absolute Monocytes – 0.4 x10^9/L (0.2 – 1.0)
Absolute Eosinophils – 0.1 x10^9/L (0.0 – 0.5)
Absolute Basophils – 0.1 x10^9/L (0.0 – 0.1)
Neutrophils – 53%
Lymphocytes – 36%
Monocytes – 8%
Eosinophils – 1%
Basophils – 1%

CRP – <3mg/L
Troponin T – <0.01ug/L

Bilirubin – 12 umol/L (<20)
Protein – 82 g/L (65 – 85)
Albumin – 46 g/L (35 – 50)
Globulin – 36 g/L (27 – 38)
Alkaline Phosphate – 93 U/L (58 – 130)
GGT – 34 (<40)
AST – 48 U/L H (<35) – Elevated
ALT – 66 U/L H (<40) – Elevated
Creatine Kinase – 82 U/L

Sodium – 144 mmo/L (130 – 145)
Potassium – 3.8 mmol/L (3.5 – 5.0)
Chloride – 103 mmol/L (95 – 105)
CO2 – 32mmol/L H – (18 – 30) – Elevated
Anion Gap – 13 mmol/L – (8 – 13)
Urea Level – 3.3 mmol/L (2.6 – 6.8)
Creatinine Level – 67 umol/L (50 – 110)
eGFR – >=90 mL/min/1.75 (normal 90 or over)

[wapf fan]

So how did you get rid of your candida?

[MetalMX]

@wapf fan 2246 wrote:

So how did you get rid of your candida?

High dose probiotics I used a probiotic from a site called custom probiotics which was excellent, Extra Virgin Coconut Oil, Candaplex a herbal candida tonic which includes milk thistle, echinacea, pau d arco, cats claw, golden seal root. Also a low carbohydrate diet which focuses on vegetables , proteins and fats with low sugar fruits.

Pretty simple. If you just have a good diet in place already you wouldn’t have any problems/symptoms in regards to candida overgrowth. But i had untreated hashimoto’s for a long time and mercury poisoning at that time thats why it developed despite having a good diet.

Incase anyone is following this thread, or if this thread is still alive. I am just right now on 50mcg of T3 and getting adrenals checked in two days via bloods. I tried T4 synthetic with T3 and my symptoms got much worse and my temp just stayed at 35.1C which is 95.18 Celcius which is discustingly low.

I have pretty much narrowed it down to having either low cortisol which was hidden due to low thyroid thats why the thyroid meds aren’t working now or Wilson’s Temperature syndrome and will treat accordingly once i get my blood tests back.

I had developed peripheral neuropathy due to long standing hypothyroidism now it has improved but the underlying adrenal or Wilson’s temp issue is still causing me severe issues. We will see which one it is.

On 50mcg of T3 split twice per day

My morning temp is: 96.2F

Afternoon temp: 95.9F

Evening temp: 95.54F

[hardasnails1973]

100 mcg of t-4 shot my rt3 up to 550 from just 220 on the old armour and t-3 combo
i felt good on t4/t3 combo you 3 weeks then the t-4 hit and then is when I knew I was in trouble. Getting adrenals checked is a good move.

[MetalMX]

@hardasnails1973 2250 wrote:

100 mcg of t-4 shot my rt3 up to 550 from just 220 on the old armour and t-3 combo
i felt good on t4/t3 combo you 3 weeks then the t-4 hit and then is when I knew I was in trouble. Getting adrenals checked is a good move.

😉

My Morning Temp is 96.8F Before Thyroid Meds. After T4/T3 meds its just drops throughout the day. I will track it today while on T3 only to see how it fluctuates.

Frequently experiencing Air Hunger and stomach tingling. Is Air hunger a symptom of low cortisol or low thyroid?

[DrMariano2]

@MetalMX 2258 wrote:

😉

My Morning Temp is 96.8F Before Thyroid Meds. After T4/T3 meds its just drops throughout the day. I will track it today while on T3 only to see how it fluctuates.

Frequently experiencing Air Hunger and stomach tingling. Is Air hunger a symptom of low cortisol or low thyroid?

After reviewing some of your posts, I have a few thoughts:

What is your ferritin level?

Thyroid and Iron both determine temperature and energy.

Adequate iron is necessary for the citric acid cycle to function in order for cells to produce ATP (Adenosine Triphosphate) – the basic storage unit for energy within cells – from the metabolism of carbohydrates, proteins, and fats. The use of ATP helps create body heat. It is made in the mitochondria.

Thyroid hormone signals cells to produce more mitochondria and larger so that more ATP can be produced. However, Thyroid hormone cannot cross cell membranes without being actively transported across. Active transport requires ATP. No iron, no ATP, no thyroid transport. Thus even adequate thyroid hormone doesn’t work without adequate cellular iron.

Mitochondrial function

Nutrient treatments to help improve mitochondrial function can be useful to improve ATP production and thus Thyroid function. The B-Vitamins, for example, are important in this regard.

Low Aldosterone and high Renin

Renin transforms Angiotensinogen into Angiotensin I.
Angiotensin I is than transformed into Antiogensin II by Angiotensin Converting Enzyme.
Antiogensin II then stimulates Aldosterone production and stimulates Symphathetic Nervous System activity.

Since Aldosterone is low, yet Renin is high, I wonder if there is some block to Aldosterone production. For example, Vitamin C is needed to produce Aldosterone. Immune System pro-inflammatory signaling can also suppress adrenal function, including reducing aldosterone production.

Levothyroxine (T4) vs. Armour Thyroid (T3+T4) vs. T4+T3 combinations

One of the problems in treating patients with T3 is that it is immediately active.

This is good in that if patients have difficulty in converting T4 to T3, T3 can be highly effective in improving function.

However, if there is preexisting excessive immune system pro-inflammatory signaling, then T3 not only improves metabolism in all cells of the body but it also specifically improves function of immune system cells. This can exacerbate/worsening already excessive immune system activity.

The increase immune system activity will then overstimulate the sympathetic nervous system – leading to anxiety, mood instability, etc.

The increase in immune system activity can suppress adrenal function. Thus, Thyroid treatment may “uncovering adrenal insufficiency” – though actually it is a contributing factor.

The increase in immune system activity may also impair thyroid signaling, at the production level in the thyroid gland or otherwise.

In the past, I observed how Armour Thyroid is more likely to cause adrenal problems than T4, with an understanding of the relationships between the nervous, endocrine, and immune system, this becomes clearer. T4 alone is much less likely to overstimulate immune system activity and the subsequent downstream signaling problems.

When suboptimal adrenal function is and excessive pro-inflammatory immune system activity is present, T4 (Levothyroxine) is much more tolerable and is preferred as a treatment.

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