Unvailed adrenal insufficency after starting Thyroid.

[hardasnails1973]

@keithdolby 1977 wrote:

How about when a compounding pharmacist makes testosterone? How realiable is this, wouldnt you also have to trust the pharmacist and not a drug manufacture?

Research the pharmacy and see who uses them. Let majority rule.
University is great.

[keithdolby]

@hardasnails1973 1978 wrote:

Research the pharmacy and see who uses them. Let majority rule.
University is great.

How do you go about researching a compounding pharmacy? There is really no place on the internet where this is discussed.

[MetalMX]

@hardasnails1973 1976 wrote:

I told you 😮
its a scam one can just use plain t-3 to get the same results and since its compounded you have no clue the accuracy of the caps. You are trusting the pharmacist not a drug manufacture. if you went to t3 you may have fried your adrenals.

Isocort is not recommended if you have high norephinpherine levels. It will make you more anxious and nervious.

The Armour Thyroid i am using is also compounded from them but so far it seems to be
working thank god.

Only second day on it but feeling much much better both physically and mentally.

I will switch to armour brand when i can find it online but stock has been nonexistant so far.

I have tried T3 by itself i used a 20mcg tablet after i developed a huge pulse, extreme weakness, difficulty breathing and feeling extremely unwell for about 3 hours until the effect faded away.

It’s highly likely i have high norepinephrine from being low thyroid all these years.
When cortisol saliva and blood work come back we will see what is going on with this and if their is issue i will only opt for HC.

Although if i was on SLT3 only while doing saliva cortisol (i think i took that armour for the first day when doing the saliva about 40mg or something with 30mcg of SLT3) this could make the results bunk as well as the blood tests? 😡

[MetalMX]

My Morning 8am cortisol is elevated.

Cortisol – 773 * (140 – 630)

Aldosterone, Renin and ACTH levels should be in tomorrow i will post them up.

[hardasnails1973]

@MetalMX 1982 wrote:

The Armour Thyroid i am using is also compounded from them but so far it seems to be
working thank god.

Only second day on it but feeling much much better both physically and mentally.

I will switch to armour brand when i can find it online but stock has been nonexistant so far.

I have tried T3 by itself i used a 20mcg tablet after i developed a huge pulse, extreme weakness, difficulty breathing and feeling extremely unwell for about 3 hours until the effect faded away.

It’s highly likely i have high norepinephrine from being low thyroid all these years.
When cortisol saliva and blood work come back we will see what is going on with this and if their is issue i will only opt for HC.

Although if i was on SLT3 only while doing saliva cortisol (i think i took that armour for the first day when doing the saliva about 40mg or something with 30mcg of SLT3) this could make the results bunk as well as the blood tests? 😡

May need alittle t-3 with armour if you start producing reverse. We find that adding 5-10 mcgs BID along with armour may be keep things in balance. I also watch for adrenal function in next 4-6 weeks as armour is increased. We check it after 6 weeks on thyroid to make sure it is not crashing adrenals. In your delicate state you need to go slow and steady changing one thing at time.

[MetalMX]

@hardasnails1973 2002 wrote:

May need alittle t-3 with armour if you start producing reverse. We find that adding 5-10 mcgs BID along with armour may be keep things in balance. I also watch for adrenal function in next 4-6 weeks as armour is increased. We check it after 6 weeks on thyroid to make sure it is not crashing adrenals. In your delicate state you need to go slow and steady changing one thing at time.

Yes i agree with changing one thing at a time.

I change one thing BAM im too exhausted to move around and just have to stay at home.

Right now i am just on thyroid, P5P and MethylB12. Folinic Acid at this particular time causes muscle weakness for me probably due to low b12 from thyroid for so long.

My peripheral neuropathy symptoms/muscle strength seem to be improving although my appetite is low but that can be attributed to low thyroid since probably a kid.

ACTH – 12 (<11)

Cortisol – 773 (120 – 620) nmol/L

So both are elevated. ACTH slightly. Renin/Aldo not back yet.

Should i add 5mcg of T3? Im afraid to add it.

It is not Armour rather a australian compounded thyroid apparently from porcine origin. Which they
simply call “thyroid extract”.

How long does it take to get the tissue levels up to somewhat normal so you are eating normally, healing normally and so forth if one is coming from a chronic hypothyroid state since childhood?

[hardasnails1973]

@MetalMX 2006 wrote:

Yes i agree with changing one thing at a time.

I change one thing BAM im too exhausted to move around and just have to stay at home.

Right now i am just on thyroid, P5P and MethylB12. Folinic Acid at this particular time causes muscle weakness for me probably due to low b12 from thyroid for so long.

My peripheral neuropathy symptoms/muscle strength seem to be improving although my appetite is low but that can be attributed to low thyroid since probably a kid.

ACTH – 12 (<11)

Cortisol – 773 (120 – 620) nmol/L

So both are elevated. ACTH slightly. Renin/Aldo not back yet.

Should i add 5mcg of T3? Im afraid to add it.

It is not Armour rather a australian compounded thyroid apparently from porcine origin. Which they
simply call “thyroid extract”.

How long does it take to get the tissue levels up to somewhat normal so you are eating normally, healing normally and so forth if one is coming from a chronic hypothyroid state since childhood?

Get the adrenal under control first before adding more thyroid in. Elevated cortiosl is easier to deal with then low cortisol. Go slow and steady and listen to dr.

[MetalMX]

Here are the rest of my the results. Thank god something is showing up.

Aldosterone – 80 pmol/L – LOW (Upright) (100 – 950)
Renin – 41 mU/L – HIGH (Upright) (3 – 40)
Aldosterone/Renin Ratio – 2 (2 – 75)

And

Cortisol – 773 HIGH (140 – 630)
ACTH – 12 HIGH (<11)

This was on just 30mcg of Slow Release T3 in the day, split 15mcg 12 hours apart.

[MetalMX]

@MetalMX 2016 wrote:

Here are the rest of my the results. Thank god something is showing up.

Aldosterone – 80 pmol/L – LOW (Upright) (100 – 950)
Renin – 41 mU/L – HIGH (Upright) (3 – 40)
Aldosterone/Renin Ratio – 2 (2 – 75)

And

Cortisol – 773 HIGH (140 – 630)
ACTH – 12 HIGH (<11)

This was on just 30mcg of Slow Release T3 in the day, split 15mcg 12 hours apart.

My saliva cortisol isn’t back yet.

[MetalMX]

It doesn’t make sense why is both ACTH and Cortisol elevated?

If one is elevated the other should be lowered is this not true?

What do my blood results indicate then?

[MetalMX]

Here are my cortisol saliva results:

That day took – 30mcg Slow Release T3 and 40mg compounded Porcine thyroid.

Salivary Hormone Test Results

DHEA-S
01 SAMPLE 03/10/09 0800 – 2.1 (0.7 – 9.4) nmol/L

CORTISOL –

MORNING SAMPLE – 0800 – 30 nmol/L
MIDDAY SAMPLE – 1200 – 27 nmol/L
EVENING SAMPLE – 1800 – 10 nmol/L
NIGHT SAMPLE – 2200 – 16 nmol/L

Female and Male Adrenal Hormone Reference and Target Ranges
Cortisol Reference Range nmol/L
Morning – 5.3 – 61.8
Afternoon – NA
Evening – 1.2 – 12.3
Night – NA

Cortisol Target
Range based on observation and feedback on thousands of salivary hormone reports
Morning – 25
Afternoon – 15
Evening – 5 – 10
Night – <5

If anything these levels are more elevated. Which might be due to isolated aldosterone deficiency.

My aldosterone was low, renin slightly elevated, and ACTH elevated slightly.

I have just done 24 hour urinary aldosterone, Cortisol, Sodium and Protein and will report these once i get these back. I am looking at Florinet as the thing that will finally help me. It would certainly explain my salt cravings, constant thirtst, weakness etc…

Maybe reverse T3 issues?. When i wake up my temperature is 36.1C and feel not too bad. When i take thyroid it starts dropping 35.7C etc… to the point where it is 35.3C in the evening and i feel terrible. This is Compounded thyroid.

Now maybe i should just look at adding regular T3 and Florinet and i will be on the road to recovery.

I’ll let HAN advise me what to do next.

[MetalMX]

If the Slow Release T3 was bogus. And it was only 40mg of thyroid i was on then these results wouldn’t be that indicative.

I took the 40mg thyroid at about 3pm.

My cortisol was 27 in the noon, then went to 10 at night. So maybe dropped from just that low dose of thyroid.

[MetalMX]

No replies?

I just got back a 24 hour urinary cortisol & sodium. Still awaiting 24 hour urine aldosterone.

Urinary free cortisol – 378 * (100 – 320)
Urinary Sodium 400 * (<100)

Sodium’s really elevated. but i have been craving salt the few days before and drinking lots of vegetable soup maybe this is because my aldosterone is low i am craving salt and drinking tonnes of fluids always.

Aldosterone – 80 pmol/L – LOW (Upright) (100 – 950)
Renin – 41 mU/L – HIGH (Upright) (3 – 40)
Aldosterone/Renin Ratio – 2 (2 – 75)

Blood Cortisol – 773 HIGH (140 – 630)
ACTH – 12 HIGH (<11)

The results are really weird. Im not sure what to make of them.

Can somebody help?

[MetalMX]

Can anybody give their thoughts on my results?

[MetalMX]

My 24hour urine aldosterone came back undetectable. Range 17-69.

Comment was: aldosterone level was undetectable or too low.

When i did my cortisol and ACTH last time both we’re elevated but i forgot to take my thyroid medication that day.

I am not sure on bloods i think even a person with addisons could draw elevated cortisol due to stress from drawing the blood which is bullshit.

Im in adrenal madness having dizziness, nausea, high pulse if i dont take in salt with water, exhaustion and so forth.

I had to go to the ER 3 times this week due to symptoms. But blood pressure was normal. Pulse was bradycardic at times.

Only think i see on bloodwork is consistently elevated liver enzymes. Which could be due to the adrenal insufficiency itself, and Low normal WBC Count which would also point to adrenal problem.

[Author]

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