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Been on LevoT for 7 weeks now and finally getting optimised. I never had this experience on armour 2 grains and am currently working out exactly what level my body needs based on how i feel.
Been taking 150mcgs for 5 weeks and reckon 125 is too low and 150 a bit too high. So alternating 125 and 150.
Had my bloods tested 2 weeks ago and i see the endo for further assessment this week. it will be a battle to get him to maintain my dose because my results were really high (good).
Any idea on how these bloods look anyone. i have no hyper symptoms, except getting a bit too hot in the last week, hence i have started to reduce down to 137.5mcgs. It may be 125mcgs is my ultimate dose, but i feel crappy if i take 125mcgs 2 days running.
Free T3 7.4 (3.5-6.6 pmol/l)
Free T4 24 (8-23 pmol/l)
TSH 0.01 (0.4-4)
On 2 grains of armour last yr my FT3 was 8.7 (so a lot higher than on levoT), but FT4 was only 16.
It seems i need a high T4 level to feel well.
@menrfrommars 1817 wrote:
Been on LevoT for 7 weeks now and finally getting optimised. I never had this experience on armour 2 grains and am currently working out exactly what level my body needs based on how i feel.
Been taking 150mcgs for 5 weeks and reckon 125 is too low and 150 a bit too high. So alternating 125 and 150.
Had my bloods tested 2 weeks ago and i see the endo for further assessment this week. it will be a battle to get him to maintain my dose because my results were really high (good).
Any idea on how these bloods look anyone. i have no hyper symptoms, except getting a bit too hot in the last week, hence i have started to reduce down to 137.5mcgs. It may be 125mcgs is my ultimate dose, but i feel crappy if i take 125mcgs 2 days running.
Free T3 7.4 (3.5-6.6 pmol/l)
Free T4 24 (8-23 pmol/l)
TSH 0.01 (0.4-4)
On 2 grains of armour last yr my FT3 was 8.7 (so a lot higher than on levoT), but FT4 was only 16.
It seems i need a high T4 level to feel well.
My current rule of thumb as a target for thyroid hormone:
1. Raise Total T4 to between 8-12 ug/dL (most important)
2. Free T3 between 330 to 420 pg/dL (multiple factors determine free T3, not just thyroid dosing).
3. TSH < 1.0Using Total T4 for Levothyroxine dosing is like using Total Testosterone to determine testosterone dosing. Just as one doesn’t use LH to determine testosterone dosing, one doesn’t necessarily need to use TSH to determine thyroid hormone dosing.
Using TSH is complicated in that one assumes a well-functioning thyroid transporter (which depends on adequate ATP production – and thus a well-functioning citric acid cycle) to transport thyroid hormone across the blood brain barrier so that it can reach the neurons in the hypothalamus and to transport thyroid hormone through the cell membrane so it can reach its nuclear receptors. It also assumes the neurons of the hypothalamus and pituitary are working well – and are not subject to aging and other metabolic problems – which is not true if one has other major illnesses such as diabetes and heart disease.
Adequate nutrition is necessary to optimize metabolism so that thyroid hormone can work. For example, without adequate iron and vitamin A and other vitamins and minerals, thyroid hormone has difficulty functioning. Without adequate cellular iron, for example, thyroid hormone may not even pass through the cell membrane to reach its receptors. Nutrition has to be optimized to optimize thyroid function.
Interestingly, if the rest of the system is optimized (e.g. psychological, psychiatric, neurologic, neuroendocrine, psychoimmunologic, metabolic, nutritional) , generally, the usual dose for Levothyroxine ends up being 100 to 200 mcg a day.
Problems in optimizing thyroid occur when there are problems in the rest of the system. For example, excessive immune system activity predisposes a person to increase sympathetic nervous system activity, palpitations, suppressed adrenal function on treatment with thyroid hormone.
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