Home Forums DISCUSSION FORUMS SIGNALS Dr. Mariano please help 3 years of tests

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  • #1396
    cobra
    Member

    Dr Mariano,

    Please help me and give me your thoughts. I will be in your area in January and want to see you. How would I go about making an appointment how far in advance would I have to do it?

    I have consistently tested low for test over this time. I have recently found a doctor that will work with me. However he wants me to see a specialist as there are “none” here locally.

    Symptoms are fatigue, depression, estrogenic fat pattern, ANXIETY……………..

    I want to feel normal again. Anxiety is killing me.

    It all started about 3 years ago when I thought I was having a heart attack. I saw my doctor and he checked my blood pressure and did an ekg. Both were okay. He ordered a blood test.

    Cholesterol 201 mg/dl <200 desirable
    Triglycerides 69 mg/dl < 150
    HDL Cholesterol 46 mg/dl < 40
    Chol/Hdl ratio 4.4 ratio < 5.0 (noted as a problem)
    Ldl Cholesterol 141 mg/dl <100optimal
    T3, total 151 ng/dl 77-178
    Free T4 1.0 ng/dl .60-1.70
    Ultrasensitive TSH 1.15 uIU/ Ml .47-5.01

    Glucose 89 mg/dl Fast: 70-99
    Bun 16mg/dl 7-18
    Creatinine 1.0 mg/dl .6-1.3
    Sodium 138mEq/l 134-145
    Potassium 4.3″ ” 3.6-5.2
    Chloride 102″” 100-108
    CO2 25″” 21-32
    Calcium 9.4″” 8.5- 10.5
    SGOT (AST) 17 IU/L 15-37
    SGPT (ALT) 50″” 30-65
    Alkaline Phosphate 62″” 50-136
    Bilirubin, Total .02 gm/dl .00-1.00
    Protein, Total 7.8″” 6.4-8.2
    Albumin 4.5″” 3.4-5.0

    Later I developed a gland under my left nipple and thought it was cancer,but it was gynecomastia. I saw a surgeon and he ordered this test.

    Cortisol 14.8 ug/dl 6-28
    Dhea 458 ng/dl 142-1410
    Total testosterone 346ng/dl 190-1037
    Estradiol 32pg/ml 20-75

    Hepatic function profile
    SGOT (AST) 21 IU/L 15-37
    SGPT (ALT) 53 ” ” 30-65
    ALKALINE phosphate 53″ ” 50-136
    Bilirubin, total .3 mg/dl .00-1.00
    Bilirubin, Direct .1 ” ” .00-.30
    Protein Total 7.1 gm/dl 6.4-8.2
    Albumin 4.2 gm/dl 3.4-5.0
    Bilirubin, indirect .2mg/dl

    I asked for a refferal to an endocrinologist and here are the test results.

    FSH 5.7MIU/Ml 1.3-19.3
    Lh 3.7MIU/Ml 1.2-8.6
    Total testosterone 230ng/dl 190-1037
    Free Testosterone 51.3 pg/ml 35-155
    Prolactin 15.7ng/ml 2.6-13.1 (noted high)
    SHBG 12nmol/l 7-49
    % free testosteron 2.15% 1.5-2.2
    Estradiol 55pg/ml <207
    (changed method of testing)

    Basic Metabolic Profile
    Glucose 95mg/dL FAST:70-99
    BUN 11mg/dL 7-18
    Creatinine 1.0mg/dL 0.6-1.3
    Sodium 139mEq/L 134-145
    Potassium 4.1mEq/L 3.6-5.2
    Chloride 104mEq/L 100-108
    CO2 29mEq/L 23-31
    Calcium 9.4mg/dL 8.5-10.5

    A few months later

    Fsh 5.1 1.3-19.3
    LH 5.7 1.2-8.6
    TT 253 250-1100
    %free test 1.87 1.5-2.2
    free test 47.4 35-155
    Prolactin 15.5 2.6-13.1

    and then about 2 months ago

    Aldosterone………………. ……11ngdl <28ngdl
    Vitamin B12……………………530 >174
    Folate, Serum………………….18. 6 >5.2
    Fsh……………………… ………5.1 1.3-19.3
    Lh………………………. ……….3.4 1.2-8.6
    Growth Hormone…………….<0.1 < or = 10
    Iron total……………………. .110 45-125
    Test total……………………. .240 250-1100
    Free %……………………….. 2.05% 1.2-2.2%
    49.2pg/ml 3.5-155
    Progesterone……………… …0.6 ng/ml .3-.9
    Ferritin…………………. …….161g/ml 25-371
    T3 total……………………. ….146 ng/ml 77-178
    anti-thyroglobulin Ab……….<20 iu/ml <20
    Free T4………………………. .1 ng/dl .6-1.7
    TSH ultrasentive tsh……….1.85 uiu/ml .47-5.01
    IGf binding protein-3………..3 mg/l 3.4-7.8
    Vitamin D(1,25 Dihydroxy)….45 pgml 15-60
    Renin Activity, Plasma………2.2 ng/ml/hr .65-5
    Cortisol, free, serum…………83 mcg/dl .07-.93 8:00am-10:00am
    Vitamin D, 25-oh total………..25 ng/ml 20-100
    (it says something about endogenous production and supplementation being indicated.)
    Vitamin D, 25-Oh, D3………..20 ng/ml
    Vitamin D, 25-OH, D2………..5
    Magnesium………………… …1.9 1.8-2.4
    Uric Acid…………………….. ..8.7 2.6-7.2

    CBC
    White Blood count………….7.6 3.8-10.8
    Red blood cell count……….5.41 4-6.20
    Hemoglobin……………….. ..15.3 14-18
    Hematocrit……………….. ….44.5 42-54
    MCV……………………… …82 82-101
    MCH……………………… …28.2 26-34
    MCHC…………………….. .34.4 32-36
    RDW……………………… ..11.9 <14.5
    Neutrophil……………….. ..52 40-80
    Lymphocyte……………….. 34 12-44
    Monocyte…………………. .9 0-12
    Eosinophil……………….. .4 0-7
    Basophil…………………. .1 0-2
    Platelet Count……………275 140-440

    Metabolic Profile
    Glucose………………..85 70-99 fasting
    BUN…………………….16 7-18
    Creatinine…………….1.1 .6-1.3
    GFR non african american..>60 Gfr< 60=chronic kidney disease
    Sodium………………139 134-145
    Potassium…………..4.3 3.6-5.2
    Chloride………………101 100-108
    CO2…………………..29 23-31
    Calcium………………..9.1 8.5-10.5
    SGOT(AST)……………..15 15-37
    SGPT(ALT)……………..40 30-65
    Akaline Phosphate……60 50-136
    Bilirubin, total…………..0.5 0-1
    Protein, total………………7.6 0-1
    albumin………………….. …4.2 3.2-5.0

    Hemoglodin A1C……………5.4 <7

    Urinalysis completely normal no problems.

    Semen Analysis
    Volume ……………………3.5 1.5-5
    Viscosity………………… ..normal
    pH………………………. .8.5 7-8
    Motility 30 min………..80 80-100
    motility 1hr……………75 80-100
    Motility 3 hr……………..70 50-100
    total count………………160 million 60-150
    morphology……………..70 >70 normal forms

    I left one paper at the doctors office from what I remember
    My cholesterol is high
    Ldl………………169 <110
    Total cholesterol 228 <200
    Hdl ??????? normal range

    total cholesterol 228 <200 triglycerides 94. <150. Hdl 47. >39. Ldl 162 <100. Ratio 4.9. <5 and dhea 324. 85-690

    I am overweight and working on that right now. I don’t understand why lh is not really elevated and my sperm count is good? Either way if test will help me feel normal again so be it. I worry about thyroid and adrenals.

    #3835
    leanguy
    Member

    @cobra 2074 wrote:

    Total testosterone 230ng/dl 190-1037
    Free Testosterone 51.3 pg/ml 35-155
    Estradiol 55pg/ml <207

    Your TT/E2 ratio is not good here… was this a sensitive (or ultrasensitive) E2 test? I’d talk to a Dr (Dr M if possible) about an AI (aromatase inhibitor) like arimidex to improve this ratio. You may end up needing HCG or testosterone as well.

    #3833

    @cobra 2074 wrote:

    Dr Mariano,

    Please help me and give me your thoughts. I will be in your area in January and want to see you. How would I go about making an appointment how far in advance would I have to do it?

    I have consistently tested low for test over this time. I have recently found a doctor that will work with me. However he wants me to see a specialist as there are “none” here locally.

    Symptoms are fatigue, depression, estrogenic fat pattern, ANXIETY……………..

    I want to feel normal again. Anxiety is killing me.

    It all started about 3 years ago when I thought I was having a heart attack. I saw my doctor and he checked my blood pressure and did an ekg. Both were okay. He ordered a blood test.

    Cholesterol 201 mg/dl <200 desirable
    Triglycerides 69 mg/dl < 150
    HDL Cholesterol 46 mg/dl < 40
    Chol/Hdl ratio 4.4 ratio < 5.0 (noted as a problem)
    Ldl Cholesterol 141 mg/dl <100optimal
    T3, total 151 ng/dl 77-178
    Free T4 1.0 ng/dl .60-1.70
    Ultrasensitive TSH 1.15 uIU/ Ml .47-5.01

    Glucose 89 mg/dl Fast: 70-99
    Bun 16mg/dl 7-18
    Creatinine 1.0 mg/dl .6-1.3
    Sodium 138mEq/l 134-145
    Potassium 4.3″ ” 3.6-5.2
    Chloride 102″” 100-108
    CO2 25″” 21-32
    Calcium 9.4″” 8.5- 10.5
    SGOT (AST) 17 IU/L 15-37
    SGPT (ALT) 50″” 30-65
    Alkaline Phosphate 62″” 50-136
    Bilirubin, Total .02 gm/dl .00-1.00
    Protein, Total 7.8″” 6.4-8.2
    Albumin 4.5″” 3.4-5.0

    Later I developed a gland under my left nipple and thought it was cancer,but it was gynecomastia. I saw a surgeon and he ordered this test.

    Cortisol 14.8 ug/dl 6-28
    Dhea 458 ng/dl 142-1410
    Total testosterone 346ng/dl 190-1037
    Estradiol 32pg/ml 20-75

    Hepatic function profile
    SGOT (AST) 21 IU/L 15-37
    SGPT (ALT) 53 ” ” 30-65
    ALKALINE phosphate 53″ ” 50-136
    Bilirubin, total .3 mg/dl .00-1.00
    Bilirubin, Direct .1 ” ” .00-.30
    Protein Total 7.1 gm/dl 6.4-8.2
    Albumin 4.2 gm/dl 3.4-5.0
    Bilirubin, indirect .2mg/dl

    I asked for a refferal to an endocrinologist and here are the test results.

    FSH 5.7MIU/Ml 1.3-19.3
    Lh 3.7MIU/Ml 1.2-8.6
    Total testosterone 230ng/dl 190-1037
    Free Testosterone 51.3 pg/ml 35-155
    Prolactin 15.7ng/ml 2.6-13.1 (noted high)
    SHBG 12nmol/l 7-49
    % free testosteron 2.15% 1.5-2.2
    Estradiol 55pg/ml <207
    (changed method of testing)

    Basic Metabolic Profile
    Glucose 95mg/dL FAST:70-99
    BUN 11mg/dL 7-18
    Creatinine 1.0mg/dL 0.6-1.3
    Sodium 139mEq/L 134-145
    Potassium 4.1mEq/L 3.6-5.2
    Chloride 104mEq/L 100-108
    CO2 29mEq/L 23-31
    Calcium 9.4mg/dL 8.5-10.5

    A few months later

    Fsh 5.1 1.3-19.3
    LH 5.7 1.2-8.6
    TT 253 250-1100
    %free test 1.87 1.5-2.2
    free test 47.4 35-155
    Prolactin 15.5 2.6-13.1

    and then about 2 months ago

    Aldosterone………………. ……11ngdl <28ngdl
    Vitamin B12……………………530 >174
    Folate, Serum………………….18. 6 >5.2
    Fsh……………………… ………5.1 1.3-19.3
    Lh………………………. ……….3.4 1.2-8.6
    Growth Hormone…………….<0.1 < or = 10
    Iron total……………………. .110 45-125
    Test total……………………. .240 250-1100
    Free %……………………….. 2.05% 1.2-2.2%
    49.2pg/ml 3.5-155
    Progesterone……………… …0.6 ng/ml .3-.9
    Ferritin…………………. …….161g/ml 25-371
    T3 total……………………. ….146 ng/ml 77-178
    anti-thyroglobulin Ab……….<20 iu/ml <20
    Free T4………………………. .1 ng/dl .6-1.7
    TSH ultrasentive tsh……….1.85 uiu/ml .47-5.01
    IGf binding protein-3………..3 mg/l 3.4-7.8
    Vitamin D(1,25 Dihydroxy)….45 pgml 15-60
    Renin Activity, Plasma………2.2 ng/ml/hr .65-5
    Cortisol, free, serum…………83 mcg/dl .07-.93 8:00am-10:00am
    Vitamin D, 25-oh total………..25 ng/ml 20-100
    (it says something about endogenous production and supplementation being indicated.)
    Vitamin D, 25-Oh, D3………..20 ng/ml
    Vitamin D, 25-OH, D2………..5
    Magnesium………………… …1.9 1.8-2.4
    Uric Acid…………………….. ..8.7 2.6-7.2

    CBC
    White Blood count………….7.6 3.8-10.8
    Red blood cell count……….5.41 4-6.20
    Hemoglobin……………….. ..15.3 14-18
    Hematocrit……………….. ….44.5 42-54
    MCV……………………… …82 82-101
    MCH……………………… …28.2 26-34
    MCHC…………………….. .34.4 32-36
    RDW……………………… ..11.9 <14.5
    Neutrophil……………….. ..52 40-80
    Lymphocyte……………….. 34 12-44
    Monocyte…………………. .9 0-12
    Eosinophil……………….. .4 0-7
    Basophil…………………. .1 0-2
    Platelet Count……………275 140-440

    Metabolic Profile
    Glucose………………..85 70-99 fasting
    BUN…………………….16 7-18
    Creatinine…………….1.1 .6-1.3
    GFR non african american..>60 Gfr< 60=chronic kidney disease
    Sodium………………139 134-145
    Potassium…………..4.3 3.6-5.2
    Chloride………………101 100-108
    CO2…………………..29 23-31
    Calcium………………..9.1 8.5-10.5
    SGOT(AST)……………..15 15-37
    SGPT(ALT)……………..40 30-65
    Akaline Phosphate……60 50-136
    Bilirubin, total…………..0.5 0-1
    Protein, total………………7.6 0-1
    albumin………………….. …4.2 3.2-5.0

    Hemoglodin A1C……………5.4 <7

    Urinalysis completely normal no problems.

    Semen Analysis
    Volume ……………………3.5 1.5-5
    Viscosity………………… ..normal
    pH………………………. .8.5 7-8
    Motility 30 min………..80 80-100
    motility 1hr……………75 80-100
    Motility 3 hr……………..70 50-100
    total count………………160 million 60-150
    morphology……………..70 >70 normal forms

    I left one paper at the doctors office from what I remember
    My cholesterol is high
    Ldl………………169 <110
    Total cholesterol 228 <200
    Hdl ??????? normal range

    total cholesterol 228 <200 triglycerides 94. 39. Ldl 162 <100. Ratio 4.9. <5 and dhea 324. 85-690

    I am overweight and working on that right now. I don’t understand why lh is not really elevated and my sperm count is good? Either way if test will help me feel normal again so be it. I worry about thyroid and adrenals.

    I see multiple issues going
    1. Vitamin D is low dangerously
    2. Low zinc levels – low alkaline phosphotase
    3. High uric acid which could be due to diabetic like state, blue eyes, gout, and copper excess should be ruled out
    4. Vitamin b-12 deficiency at tissues.
    5. Potential cortisol imbalance that need to be ruled out via ASI
    6. One needs to see a complete thyroid panel including ft3 levels as well as one you have noted.
    7. I would also look if this is primary or secondary hypogonadism or from other causes such as nutrient imbalances.

    #3837
    cobra
    Member

    @leanguy 2079 wrote:

    Your TT/E2 ratio is not good here… was this a sensitive (or ultrasensitive) E2 test? I’d talk to a Dr (Dr M if possible) about an AI (aromatase inhibitor) like arimidex to improve this ratio. You may end up needing HCG or testosterone as well.

    Maybe ai and bromo plus the weight loss?

    I used to not want test, but lately I don’t care I just wanna feel normal again.

    I know you from the minds. I had to change my name some people at work found out I was posting there so I’ll be using this tag from now on.

    #3838
    cobra
    Member

    @hardasnails1973 2081 wrote:

    I see multiple issues going
    1. Vitamin D is low dangerously
    2. Low zinc levels – low alkaline phosphotase
    3. High uric acid which could be due to diabetic like state, blue eyes, gout, and copper excess should be ruled out
    4. Vitamin b-12 deficiency at tissues.
    5. Potential cortisol imbalance that need to be ruled out via ASI
    6. One needs to see a complete thyroid panel including ft3 levels as well as one you have noted.
    7. I would also look if this is primary or secondary hypogonadism or from other causes such as nutrient imbalances.

    Hi Hans,

    I spoke to you on the minds and through email my wife is currently pregnant.

    Anyway I changed my name cuz people at work found out my name and it’s kinda embarassing so….

    I may not be able to afford to make the trip out to see you. We are barely going to be able to make it to cali with ticket, hotel, visit, tests…..

    I followed your suggestion on supplementing I think it was 20,000 ius of vitamin d ( I use vitamin d3) for two weeks and currently am taking only 5,000ius a day + more sun light.

    I take 50mgs chelated zinc every night with one tablespoon evo (gonna switch to coconut).

    I take a mulit, hawthorne berry, celery seed extract, calcium w vitamin d & k, fish oil.

    I also supplement fiber with orange sugar free metamucil 3 times daily.

    I am down 10 pounds since restarting high protein low carb. Originally I thought I was 300 pounds turns out I got up to 320 now I am at 310.

    Basically I eat steak, chicken, and broccoli daily. Sometimes sugar free jello. Occasional diet coke, green tea and water.

    Every three days I give myself a cheat day. Reconsidering this, because I really don’t like going back into ketosis and I feel much better when I am in.

    Sleep needs work.

    What do you think could be causing my vitamin and mineral defficences? Diet or digestive problems?

    #3834

    @cobra 2087 wrote:

    Hi Hans,

    I spoke to you on the minds and through email my wife is currently pregnant.

    Anyway I changed my name cuz people at work found out my name and it’s kinda embarassing so….

    I may not be able to afford to make the trip out to see you. We are barely going to be able to make it to cali with ticket, hotel, visit, tests…..

    I followed your suggestion on supplementing I think it was 20,000 ius of vitamin d ( I use vitamin d3) for two weeks and currently am taking only 5,000ius a day + more sun light.

    I take 50mgs chelated zinc every night with one tablespoon evo (gonna switch to coconut).

    I take a mulit, hawthorne berry, celery seed extract, calcium w vitamin d & k, fish oil.

    I also supplement fiber with orange sugar free metamucil 3 times daily.

    I am down 10 pounds since restarting high protein low carb. Originally I thought I was 300 pounds turns out I got up to 320 now I am at 310.

    Basically I eat steak, chicken, and broccoli daily. Sometimes sugar free jello. Occasional diet coke, green tea and water.

    Every three days I give myself a cheat day. Reconsidering this, because I really don’t like going back into ketosis and I feel much better when I am in.

    Sleep needs work.

    What do you think could be causing my vitamin and mineral defficences? Diet or digestive problems?

    Thyroid issues and excessive body fat
    The body if having high enough body fat it will recongnize fat as another organ causes nutrients to be used at a higher rate.

    #3836
    JanSz
    Member

    @cobra 2087 wrote:

    Cortisol, free, serum…………83 mcg/dl .07-.93 8:00am-10:00am
    Uric Acid…………………….. ..8.7 2.6-7.2
    Total testosterone 230ng/dl 190-1037
    Prolactin 15.7ng/ml 2.6-13.1 (noted high)
    SHBG 12nmol/l 7-49
    Every three days I give myself a cheat day.

    Work in above.

    Replace cheat day with day where you just drink tap water.
    .

    #3839
    cobra
    Member

    @hardasnails1973 2108 wrote:

    Thyroid issues and excessive body fat
    The body if having high enough body fat it will recongnize fat as another organ causes nutrients to be used at a higher rate.

    So do you think if I continue to lose weight and treat whatever thyroid issues and if any adrenal issues my test could normalize?

    #3840
    cobra
    Member

    @JanSz 2111 wrote:

    Work in above.

    Replace cheat day with day where you just drink tap water.
    .

    Hi JanSz

    What is wrong with my morning cortisol level?

    Uric Acid I agree. I was told what it is caused by, but with doing low carb (around 20grms aday) high protein would this improve or get worse? I have trouble losing weight unless I’m in ketosis. I have had no other diet plan that worked as well as a keto diet. If a keto diet would make it worse is it worth it given how much weight I need to lose? I worry about my heart. You suggested a diet I should follow on the minds and I have been following one that is very close to it minus the steamer.

    Testosterone is low. Do you think weight loss would raise it or fixing other issues like hans is saying?

    Prolactin is high. I took bromo for a while. at first I felt a difference, but after a while it just made me feel dizzy and not much else.

    Shbg is low. Is this a problem? I know it’s because I’m fat so I am already working on that. With weight loss would it raise with testosterone or by itself?

    For the cheat day I meant every three weeks not three days. I set goals and if I don’t reach them I don’t take the cheat days.

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