Home Forums DISCUSSION FORUMS GENERAL HEALTH Desperatey need Help…Messed up my hormones…only 21

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  • #1535
    boatnerj
    Member

    Hey guys. I started a post over at musclechatroom and people have been giving me advice.
    They also told me to post here to try and get as much light shed on this as I can.

    Hey guys. I am a 21 year old male. I am 5 10 and weigh 123 pounds (you will find out why so low if you keep reading 😛 )

    This all started back in my senior year of high school. I ended up getting mono/hepatits during cross country season without even realizing it. We ran anywhere from 60-70 miles a week. After the season ended we discovered I hadboth of those.

    After I “recovered”, I continued to run on my own (still around 50 miles a week). I always felt tired and continued to make myself run everyday. I never lost weight or anything, I just never allowed myself to recover. I also think that while I was eating enough calories I may not have been getting enough nutrition (the right vitamins/minerals/etc).

    My energy continued to slowly decline at a very slow pace.

    My first year of college I continued to run 30-40 miles a week for a runners club, and also lifted weights
    6 times a week. Along with the weight lifting I began taking these pre-workout nitric oxide/energy drinks that are loaded with caffeine and other stimulants (and continued to take them every day up until maybe a month or so ago, so for 2-3 years!).

    By the next year I no longer had enough energy to run much anymore, but I continued to lift and take the pre-workout energy drinks.

    The following summer is when I developed the bad constipation. I never got over it and for the past 2 years I have had to use my finger in the morning to stimulate a bowel movement (otherwise I dont go for 4-5 days). Nothing I have done has fixed my symptoms, not going dairy or gluten free, using digestive enzymes, supplementing with magnesium/selenium/zinc, eating lots of raw veggies an fruit, cultured fermented veggies, coconut oil, raw butter, not even colonics. The colonoscopy and endoscopy ruled out any thing wrong in the intestines and stomach itself, no celiacs, no cancer/diverticuli/etc, healthy vili. Anal rectal manometry and bio feedback indicate nothing I wrong with the way I have a bowel movement either.

    Now all along I have been treating the constipation as the cause of my fatigue/sluggishness, dry skin, non existent sex drive, difficulty getting erections, very weak erections, almost no semen production, low body temp (around 96.9/97 in mornigs-97.4 or so in he afternoon and at night…but stable, doesnt wildly fluctuate), etc. However, after reading online about thyroid and adrenal problems I think the constipation is just another symptom.

    I went to my docs and they drew some blood.

    TSH was 6.01 (0.27-4.20),
    free t4 was 1.030 (1.01-1.79).
    IGG 875.5 (700-1600)
    IGA 112.4 (70-400)
    IGM 199.3 (40-230) WHat do these represent?
    Thyroglobul AB <20 (<20)
    thyroid per AB <10 (<35)

    They put me on trial of syntrhroid and after about 2 months of 50 mcg a day then 2 months of 100 mcg a day my TSH was at 1.20 and m4 ft4 was up to 1.36. I still had all the symptoms though.

    I found STTM and began doing research. I tried to get them to look at ft3 an other things but they wouldn’t listen.

    I have now had mary shomons breakthrough done along with testosterone (total). The results were

    Test Name Flag Result Ref Range Units
    Glucose 80 65-99 mg/dL
    Uric Acid 3.2 2.4-8.2 mg/dL
    BUN 26 5-26 mg/dL
    Creatinine 0.92 0.76-1.27 mg/dL
    eGFR >59 >59 mL/min/1.73
    eGFR AfricanAmerican >59 >59 mL/min/1.73
    BUN/Creatinine Ratio HIGH 28 8-27
    Sodium 140 135-145 mmol/L
    Potassium 4.5 3.5-5.2 mmol/L
    Chloride 104 97-108 mmol/L
    Calcium 9.2 8.7-10.2 mg/dL
    Phosphorus 3.6 2.5-4.5 mg/dL
    Protein, Total 6.4 6.0-8.5 g/dL
    Albumin 4.6 3.5-5.5 g/dL
    Globulin, Total 1.8 1.5-4.5 g/dL
    A/G Ratio HIGH 2.6 1.1-2.5
    Bilirubin, Total 0.5 0.0-1.2 mg/dL
    Alkaline Phosphatase, S 83 25-150 IU/L
    LDH 144 100-250 IU/L
    AST (SGOT) 34 0-40 IU/L
    ALT (SGPT) 52 0-55 IU/L
    GGT 51 0-65 IU/L
    Iron 77 40-155 ug/dL
    Cholesterol, Total 159 100-199 mg/dL
    Triglycerides 31 0-149 mg/dL
    HDL Cholesterol 79 >39 mg/dL
    VLDL Cholesterol Cal 6 5-40 mg/dL
    LDL Cholesterol Calc 74 0-99 mg/dL
    T. Chol/HDL Ratio 2.0 0.0-5.0 ratio units
    Estimated CHD Risk < 0.5 0.0-1.0 times avg.
    TSH 2.950 0.450-4.500 uIU/mL
    Testosterone LOW 115 280-800 ng/dL
    LH LOW 0.5 1.7-8.6 mIU/mL
    Vitamin D, 25-Hydroxy 37.6 32.0-100.0 ng/mL
    T4,Free(Direct) 1.23 0.82-1.77 ng/dL
    Prolactin 9.5 4.0-15.2 ng/mL
    Estradiol 15.0 7.6-42.6 pg/mL
    DHEA-Sulfate 455.3 211.0-492.0 ug/dL
    FSH 2.3 1.5-12.4 mIU/mL
    Progesterone 0.9 0.2-1.4 ng/mL
    Thyroid Peroxidase (TPO) Ab 17 0-34 IU/mL
    Triiodothyronine,Free 2.1 2.0-4.4 pg/mL

    After only two weeks of being off synthroid my TSH is already going back up, and like I suspected my freet3 is at the very bottom of its range. I am also essentially castrated testosterone wise.

    We then did a more detailed testosterone workup and got the following
    We got the testosterone workup back and I am worse off then we thought

    Name Value Reference Range
    TESTOSTERONE 67 241-827
    SEX HORM BIND GLOBULIN 40 13-71
    CALC. FREE TESTOSTERONE
    1.1 6.0-27.0

    Reading online it seems having low lh and low fsh along with low testosterone indicates something wrong with the pituitary or hypothalamus. How does this link up with thyroid? And does the fact that I had mono put me at a greater risk of having the hashimotos disease (an could that be causing all my problems?)

    Does such a high DHEA-S indicate any adrenal problems?

    I am doing the salivary cortisol test today and will mail it in tommorow.

    I don’t “feel” as if I have adrenal problems, I can go to the gym 4-5 times a week, and walk 3 miles a day and not feel super fatigued or anything. I have no trouble sleeping, no waking up at night, sleep gives me some energy back, but not as much as it should (though the fact it refreshes me a bit is a good thing…no adrenal exhaustion at least, if anything only mild). The only thing that had me suspecting adrenals as well is my history (running is definitely harsh on adrenals and all the energy/nitric oxide drinks).

    My D3 levels were also pretty low but I take a lot of cod liver oil and am good about supplementation.

    Would it be wise to check any other vitamins/minerals to see if there is any degree of malabsorption going on?

    I am awesome about nutrition and supplementation (magnesium = 800-1000 mg, vit c = 4-5 grams throughout the day, zinc, selenium, b-12, digestive enzymes, probiotics, lots of sea vegetables, granulated kelp, etc).

    The worse symptom to me both mentally and physically is the constipation. I just don’t get the urge to go for 3 days, sometimes 4, and when I do go I just ont feel like I have a lot of push/power in expelling the crud. It also comes out in soft narrow pellets, so it may just be squeezing past older harder feces..

    I need to put back some weight (since the constipation started two years ago I have gone from 135ish to about 123).

    I am eating very high healthy fats (rich in vitamins too) to keep things as calorie dense as possible while still getting in goo amounts of fruit/veggies/fiber. I also have a thing of meat (lean meat, fatty red meat, or salmon) every day along with a scoop of goat milk or egg white protein powder. I cant gain weight eating close to 3000 calories a day and I dont burn a lot of calories in activities.

    I have been giving myself a 64 ounce enema on advice from my colonic lady as well as a naturopath just so I can keep things from stagnating, becuase being constipated sure as shi* (pun intended) wont help my situation. I stopped using my finger because I hought I had gotten my body addicted to it, but all the finger had been doing all along was stimulating peristalsis, which wasnt working because of the hypo stuff.

    I just had blood work done this mornig for ACTH, 8 AM serum cortisol (still waiting for results for a 24 hour saliva test), and we re-did LSH ans FSH to check.

    #4320
    boatnerj
    Member

    This is a response I got from another member on the forum who referred me to this site.

    “I am sorry I did not get to this I had people here from out of town a death in the family.

    I see your problem all the time young men over doing it working out and exercising. Your LH and FSH are very low with low Testosterone is telling me you have shut down your pituitary or hypothalamus.

    Now your Estradiol levels are very low because your Testosterone is so low you make Estradiol from Testosterone.

    To make sure this is what happened you need an MRI on your Pituitary to rule out a tumor. Have you every had a head injury this can do this also. I am Hypopituitary due to a head injury. In my case my Testosterone is low with my Cortisol my Adrenals work just don’t get told to work. My TSH messages are still sent from my Pituitary I am off Thyroid meds and my TSH went up to 5.7.

    If you go on TRT Testosterone meds this will shut you down even more and you can end up on this for life.

    You can do a Clomid or HCG Stim. test to see if your testis still work and if they do just take HCG this will act like the LH and make your Testis make Testosterone and not shut you down for life. As you fix what is wrong later on you can come off the HCG and see if your body jumps back in and makes it’s own Testosterone. Having low Testosterone will stress your Adrenals and you end up with them over worked.

    You need to see a good Dr. for this one I know for sure that can fix is you Dr. John in MI. men fly or drive out to see him they only need to see him once to get treated the rest he can do by phone. Or see if one of your Dr.’s will work with him over the phone to test and treat you he dose this also.
    http://www.allthingsmale.com
    He has a forum you can to join and post your labs and get some input from the Dr.’s at his site that are sick like you.
    http://www.musclechatroom.com/forum/for … ay.php?f=2

    I feel what is wrong with you is you over did it exercising and working out then you got sick and kept this up shutting down your hormones.

    Stop doing this exercising until you figure out what is wrong and what you need to fix it. If you Adrenals are over worked doing this will make them worse.

    You need not go on Testosterone meds because your brain will shut you down for ever and you will need it for life. You can get your Testosterone levels up with HCG doing 100 IU’s in a shot everyday. But see Dr. John
    Read this link in this is the Clomid or HCG stim. test.
    http://www.aace.com/pub/pdf/guidelines/hypogonadism.pdf

    We have been helping a young boy 16 that did what you did go get down in a weight class for state Wrestling but his partents would not get him to the right kind of Dr. for a dam long time.

    With low Thyroid your stomach will not digest your food right you need to first see how your Cortisol levels look if low fix this first then do Thyroid you need Cortisol to carry the Thyroid hormones out of your blood in to your cells if your levels are to low the Thyroid meds will just build up in your blood and make you sicker.”

    #4321
    boatnerj
    Member

    Got some more test results back, input welcome

    Test Name Flag Result Ref Range Units Graph Info
    LH LOW 0.8 1.7-8.6 mIU/mL
    Cortisol HIGH 20.3 2.3-19.4 ug/dL
    ACTH, Plasma 23.9 7.2-63.3 pg/mL
    FSH 2.7 1.5-12.4 mIU/mL
    progenelone, serum 53 (23-173 ng/dl)
    ferritin 107.8 (22-322ng/dl)

    #4322
    boatnerj
    Member

    I dont know if through the chronic over exxercising/low weight I managed to throw off my HPA axis or what. I am scheduled to see Dr Crisler either this week or next.

    Hopefully addressing thyroid/adrenal problems will, along with time, be all that is required, but how likely o you guys think it is I will need to try a re-start of my HPA axis or any type of hormonal treatment?

    #4323
    boatnerj
    Member

    Some interesting reads regarding my situation

    http://www.ergo-log.com/clomidendur.html

    #4324
    boatnerj
    Member

    More

    “Functional Hypogonadism With High Athletic Stress And Low T”

    According to research presented at the Endocrine Society’s annual meeting, “males presenting with high athletic stress or weight loss, coupled with low testosterone, may signal the rise of a new disorder — functional hypogonadotrophic hypogonadism.”

    In a study of seven patients and 35 healthy matched controls, researchers found that the “patients had a lower average weight compared to controls (64.1 kg versus 79.9 kg, P<0.01). They also had a lower body mass index (20.7 versus 24.9, P<0.01) and a lower percentage of body fat (9.8% versus 17.6%, P<0.01)," in addition to "lower serum testosterone…(168 ng/dL versus 534 ng/dL, P<0.001), lower serum estradiol (12.4 pg/ml versus 37.5 pg/ml, P<0.001), and lower serum leutinizing hormone (LH) (7.2 IU/L versus 9.9 IU/L, P<0.05)."

    ENDO: Pursuit of Six Pack Abs May Trigger New Malady
    Medical News: ENDO: Pursuit of Six Pack Abs May Trigger New Malady – in Meeting Coverage, ENDO from MedPage Today

    SAN DIEGO — Males presenting with high athletic stress or weight loss, coupled with low testosterone, may signal the rise of a new disorder — functional hypogonadotrophic hypogonadism.

    Just as women whose bodies are under stress from excessive exercise, weight loss, or psychological stress can experience hypothalamic amenorrhea, a seven-patient series suggests that a similar phenomenon may exist among men undergoing similar kinds of stress, Andrew Dwyer, MD, of Massachusetts General Hospital, said during a poster session here at the annual meeting of the Endocrine Society.

    “We saw some male patients who all have a similar type of presentation in terms of one or more of this [stress] triad, and presented with low testosterone,” Dwyer explained. The patients all had normal puberty and a normal testicular size, but all presented with “vague, non-specific symptoms” of low testosterone, including absent morning erections, low energy level, fatigue, decreased athletic performance, and decreased libido, he said.

    “Interestingly, two of these patients had female family members with amenorrhea, which made us think maybe there’s a connection,” Dwyer continued.

    To further study this phenomenon, the patients were recalled to the hospital, where they underwent detailed genotyping and phenotyping, including measurements of reproductive and metabolic hormones, an overnight frequent sampling study of leutinizing hormone, and DEXA scan for body composition. The investigators also recruited 35 age-matched healthy adults as controls.

    The seven patients had a lower average weight compared to controls (64.1 kg versus 79.9 kg, P<0.01). They also had a lower body mass index (20.7 versus 24.9, P<0.01) and a lower percentage of body fat (9.8% versus 17.6%, P<0.01).

    In terms of their biochemical characteristics, the patients had lower serum testosterone compared with controls (168 ng/dL versus 534 ng/dL, P<0.001), lower serum estradiol (12.4 pg/ml versus 37.5 pg/ml, P<0.001), and lower serum leutinizing hormone (LH) (7.2 IU/L versus 9.9 IU/L, P<0.05).

    The patients also had lower pulse frequency, lower mean LH amplitude, and lower serum FSH, but none of those numbers approached statistical significance, according to the investigators.

    Despite their low testosterone levels, six of the seven patients had LH pulse patterns, frequency, and amplitude that were no different from controls, Dwyer said. However, the seventh patient had four hours of no pulses, then a burst of three pulses, then no pulses for the remaining four hours, a pattern that normally occurs when boys first enter puberty.

    “It’s as if this patient is recapitulating an early- to mid-pubertal LH pulse secretion pattern,” he said. “He’s 17, he went through normal puberty, he’s done and he’s virilized, but with the stress of exercise and the weight loss, perhaps the stress tipped him back into the nocturnal pulse pattern.”

    Dwyer noted that after the patients had been tested, one of them sustained a heel injury and had to stop training for a while. “He gained six pounds, and we measured his testosterone level, and serially, it stayed normal,” he noted. “So with just enough removal of stress…he was able to swing back into normal testosterone production.”

    Another patient who decreased his training upon the researchers’ recommendation was also retested and his testosterone level was up into the low end of the normal range, said Dwyer.

    The researchers are calling the possible new disorder functional hypogonadotrophic hypogonadism. “In Boston, there are lots of marathon runners and collegiate rowers who exercise a lot and don’t exhibit these symptoms,” he said. “So what is it about these seven men that make them different from vast majority of superexerciser lean guys?”

    The investigators hypothesize that these men may harbor mutations in genes that are involved in GnRH androgyny or reproductive access such that with the right stressor, that can tip them into hypogonadism, but if you remove the stressor they tip back,” said Dwyer.

    Rick Dorin, MD, chief of endocrinology at the University of New Mexico, in Albuquerque, said the study was very interesting.

    “I see a painfully large amount of hypogonadism in in my clinical practice at the Veterans Affairs Hospital,” said Dorin, who was not involved in the study. “We see a lot of hypogonadism due to other factors, but not in such young men. This is raising the possibility that the [hypothalamic amenorrhea] in women athletes — that a comparable thing goes on in young men. They’ve got provocative findings in a small number of patients.”

    Primary source: The Endocrine Society
    Source reference: NR Chavan, AA Dwyer, PW Butler, MT Collins, GP Sykiotis, KW Keefe, SB Seminara, L Plummer, WF Crowley, N Pitteloud. “Male functional hypogonadotropic hypogonadism (MFHH): A distinct clinical entity?” ENDO 2010; Abstract Book, P2-462

    #4316
    DrMariano2
    Participant

    Based on the information you present, the following seem evident:

    Symptoms:
    Constipation
    Loss of energy
    Dry skin
    Loss of libido
    Low body temperature
    Weight Loss

    Labs are incomplete.
    It would be nice to have:
    Total T4
    Reverse T3
    Ferritin
    Vitamin A
    Vitamin B12, Folate
    Plasma Fractionated Catecholamines
    Fasting insulin – or even a 3-hour glucose tolerance test measuring glucose, insulin, and glucagon at hourly intervals after a 75 gram glucose load.
    H. Pylori

    Obvious Findings:
    Hypothyroidism
    Hypogonadism
    Low Blood Sugar

    The question is why do you have these problems? For this, further medical evaluation is necessary.



    STTM = Stop The Thyroid Madness.com (it is best to expand on your abbreviations).

    DHEA in a young man can be between 400 to 500 ug/dL

    In regard to adrenal function, the question would be: In relationship to the stress level, is adrenal function adequate? If not, then perhaps adrenal function is being suppressed. For example, if stress is high, cortisol should be relatively elevated. Weight-lifting, for example, is a strong stress to the body. Is the cortisol level adequately elevated after lifting weights, even the day after?

    Generally, half of the dry weight of feces are probiotic bacteria. Thus if constipation is present, the question is whether or not a person has adequate intestinal flora.

    Constipation can be a symptom of suboptimal thyroid signaling.

    Adequate nutrition such as the B-vitamins, Vitamin A, iron, Selenium are necessary for thyroid hormone to function. Immune system pro-inflammatory signaling can also impair thyroid function.

    If many pituitary hormones are low, then there is the possibility of a pituitary tumor affecting function. However, TSH at one time was very high – helping negate that idea.

    Note that for many patients, treatment with Levothyroxine is fine, even those who appear thyroid resistant. It is, however, important to optimize nutrition, metabolic function, nervous system, and immune system function to optimize one’s ability to convert T4 to T3, and one’s ability to transport thyroid hormone across cell membranes to its receptor, and to optimize thyroid receptor function. That can be complicated but the associated techniques allow one to use Levothyroxine well in practically any person without having to use T3. I arrived at that conclusion when I was forced to use only Levothyroxine in many patients because T3 and Armour were absolutely not available to them. I had to figure out how to make it work.

    Best,

    Dr. M

    #4325
    boatnerj
    Member

    I have come to accept the fact that I had an eating disorder of some kind. While I never starved myself, I way overexercised and didnt eat near enough to fuel my activity. Over time it took its toll and my bowels were the first to go!

    I hovered around a weight of 120 lbs for about 1.5 to two years and now seeing a psychiatrist as well as gaining a solid 0.5-1 lbs a week. The past 4 days I have gone on my own in the morning to some degree, and have been relyying on enemas less and less. I am only up to 124 now but I am already feeling better and seeing small progress.

    WHat I am worried about now is the testosterone. In anorexic males it is very low, and i seems to rise back up with weight gain, but usually doesnt ever return to normal, and at best reaches low normal (most studies I have read have observed this, even after several years of follow up following weight restoration). While I never lost extremem amoutns of weight, and the most I ever weighed was around 135 lbs, I have hovered around 120 for so long I am now scared that my testosterone will be shot for the rest of my life. I know of several other males in my same situation who after years of feeling like crap even after weight restoration had to finally go on trt (I would rather do this then feel bad with low t).

    Have you ever worked with, or can you comment on eating disorders and testosterone? I have been granted a year off to get better before attending medical school, and Dr Crisler will be attempting to get my test going again on its own via some methods (including me gaining weight obviously), but if it comes to it I may have start T injections. I would prefer feeling good again and being able to be the best I can in medical school while taking T shots, then having various aspects of my life suffer due to lower testosterone.

    Thank you Dr. M.

    #4326
    boatnerj
    Member

    Other tests

    Celiacs

    gliadin IGG………..13 High (0-10)
    gliadin IGA…………1 (0-10)

    TTG IGA…… <1 (0-4)

    ENDOMY IGA…….negative
    TOTAL IGA…….139 (44-441)

    Results may support a diagnosis of celiac disease but are not specific.

    IgG serological markers for celiac isease detected.

    AGA IgG elevations with IgA deficiency indicates that celiac disease is probable. AGA IgG elevations with normal total IgA occur in normal individuals as well as other GI conditions. HLA typing may be helpful.

    T3, REVERSE 436 90-350
    ferritin 107.8 (22-322ng/dl)

    Also attached a cortisol stress test

    All pretty much correlates with values associated with eating disorders/excessive exercise

    #4327
    boatnerj
    Member

    I know time and food will be the main thing that will heal me. I am just worried now I will feel like garbage forever, never be able to become muscular, etc.

    One thing I was mainly worried about (not being able to poop normally again on my own) is already showing some progress after only 3-4 weeks of eating a minimum of 3000 calories a day. Hopefully my body just shut off my colon due to the malnutrition and with time it will start the factory up again (seems most likely….my gastroparesis and bloating after every single meal are now basically gone)

    #4317
    DrMariano2
    Participant

    @boatnerj 2944 wrote:

    I have come to accept the fact that I had an eating disorder of some kind. While I never starved myself, I way overexercised and didnt eat near enough to fuel my activity. Over time it took its toll and my bowels were the first to go!

    I hovered around a weight of 120 lbs for about 1.5 to two years and now seeing a psychiatrist as well as gaining a solid 0.5-1 lbs a week. The past 4 days I have gone on my own in the morning to some degree, and have been relyying on enemas less and less. I am only up to 124 now but I am already feeling better and seeing small progress.

    WHat I am worried about now is the testosterone. In anorexic males it is very low, and i seems to rise back up with weight gain, but usually doesnt ever return to normal, and at best reaches low normal (most studies I have read have observed this, even after several years of follow up following weight restoration). While I never lost extremem amoutns of weight, and the most I ever weighed was around 135 lbs, I have hovered around 120 for so long I am now scared that my testosterone will be shot for the rest of my life. I know of several other males in my same situation who after years of feeling like crap even after weight restoration had to finally go on trt (I would rather do this then feel bad with low t).

    Have you ever worked with, or can you comment on eating disorders and testosterone? I have been granted a year off to get better before attending medical school, and Dr Crisler will be attempting to get my test going again on its own via some methods (including me gaining weight obviously), but if it comes to it I may have start T injections. I would prefer feeling good again and being able to be the best I can in medical school while taking T shots, then having various aspects of my life suffer due to lower testosterone.

    Thank you Dr. M.

    I am a psychiatrist. Eating disorders are mental illnesses and are relatively common among the patients I treat. So is body dysmorphic disorder.

    Being around 21 years-old, 70 inches tall and 120 pounds is NOT that unusual. Height is 98th percentile. Weight is around 40th percentile. When metabolism slows down A LOT when one reaches 25 years old can result in 30 pounds of weight gain. That would increase weight to around the 80th percentile.

    In my medical school class, most medical students GAINED 30 pounds. We called our intramural basketball team the Pot Bellies. Heavy studying leaves little for other activities. Slowing metabolism in one’s mid 20’s contributes to the weight gain.

    If a person wants to be slim, he or she would choose to do a lot of aerobic exercise. One can’t gain muscle mass with such exercise. That’s why marathon runners, soccer players, pro cyclists, and pro basketball players are usually ectomorphs.

    Anorexia can cause significant systemic problems. Cholesterol can be extremely high, for example, in part due to deficiencies of cholesterol-based hormones. Non-thyroid illness disrupting thyroid function may occur. Nutrient deficiencies contribute to hormonal problems and other systemic problems.

    A TSH > 4.0 indicates very significantly deficient thyroid hormone signaling in the brain compartment, which may correlate with the body compartment when the actual thyroid hormone levels are compared. However, the two may diverge also since the two compartments can each have their own thyroid hormone levels.

    Constipation is a common symptom of hypothyroidism.

    Hypogonadism may be caused by hypothyroidism and nutrient deficiencies. When significant, I would consider treating hypothyroidism and nutrition first in order to self-correct at least part of hypogonadism, if not all of it.

    If there is serious nutritional deficiency, it may be highly important to address nutrition first to see if thyroid hormone signaling problems will self-correct. It is a chicken-and-egg problem however since hypothyroidism can predispose a person to eating disorders and other mental illnesses.

    Often, thyroid hormone is intolerable when there is significant immune system inflammatory activity. If so, I would look for and address the cause(s) of this in order to lay the groundwork for adding thyroid hormone.

    Food sensitivities, Celiac disease, suboptimal intestinal flora can lead to systemic inflammatory signaling. Once this spreads to the nervous system, sickness behavior may be triggered. This includes lack of energy, loss of motivation for activities, mood disorders, etc. etc.

    #4328
    boatnerj
    Member

    Are you in agreement with me though, that pretty much all of my lab values corrspond to just years of malnourishment and overexercise? Studies of ARMY rangers being out through camp and exposed to malnourishment had pretty much the same patterns of thyroid, adrenal, and sex hormones as I have now.

    And when you say to nutritionally evaluate me would that involve something the nutreval test or ONE?

    ANd would it be wise to try and put me on some type of testosterone replacement therapy since I am experiencing so man y negative ffeedbacks from the malnourishment (I only have a year to get as healthy as I can) and then sometime down the road try a PCT protocol and see where my levels come out (after my hormones have been at a more optimal level for a length of time an I have gained weight)? WOuld testosterone help with repairing and restoring faster what the anorexia damaged?

    #4318
    DrMariano2
    Participant

    @boatnerj 2950 wrote:

    Are you in agreement with me though, that pretty much all of my lab values corrspond to just years of malnourishment and overexercise? Studies of ARMY rangers being out through camp and exposed to malnourishment had pretty much the same patterns of thyroid, adrenal, and sex hormones as I have now.

    And when you say to nutritionally evaluate me would that involve something the nutreval test or ONE?

    ANd would it be wise to try and put me on some type of testosterone replacement therapy since I am experiencing so man y negative ffeedbacks from the malnourishment (I only have a year to get as healthy as I can) and then sometime down the road try a PCT protocol and see where my levels come out (after my hormones have been at a more optimal level for a length of time an I have gained weight)? WOuld testosterone help with repairing and restoring faster what the anorexia damaged?

    I have no agreement with you since I do not know who you are nor have I examined you myself nor do I have all of the information necessary.

    The term “just” is often an attempt to minimize attribution when other solutions may also coexist. The answer is often more complicated.

    There are many paths to the same set of lab test patterns. And there can be various outcomes to the same set of lab test patterns. For example, the same set of lab test patterns can result in obesity in most people, yet anorexia in others.

    Lab tests are inevitably incomplete data sets, that do not tell the whole story of why a person ends up the way they do.

    Since you have not identified yourself as an Army Ranger, then a study on Army Rangers may not apply to you, the individual.

    Studies on groups of people do not necessarily apply to the individual, particularly when there is a statistical distribution of outcomes.

    Correlation does not imply causation. Similarities do not imply causation.

    “Pretty much” is a vague term that leaves room for error, inaccuracy, or an outcome opposite of that discussed.

    Nutritional assessment may include obtaining a person’s dietary history, current diet, and some lab tests out of many to determine nutrient deficiencies that may be present. Not all nutrient deficiencies can be tested since there may not be a test for certain ones.

    Addressing a testosterone deficiency may be useful to help improve a person’s physiologic state. It is important to determine what underlying condition(s) may underlie the testosterone deficiency. For example, if testosterone deficiency is primarily due to hypothyroidism and malnourishment, then it may be useful to address these problems first in order to correct what can be corrected before adding an additional treatment.

    At times, for example, adding testosterone before addressing hypothyroidism can have negative effects since exogenous testosterone can also lower thyroid hormone signaling. This is why some patients cannot tolerate exogenous testosterone despite being hypogonadal. Ideally, the foundation for an intervention is set to allow a positive outcome.

    The risks versus benefits of an intervention need to be considered to help one decide on how to proceed.

    Wisdom is the ability to improvise based on knowledge and skills gained from experience.

    #4319

    Boat.
    I have replied to several of your posts.
    First step as Dr. M mentioned is why these are occurng.
    Second step is to do a proper hormone evaluation with a good Dr.
    Third is to identify the imbalances in your lifestyle, sleep patterns,nutrition, or other hidden stressor. This is where the nutraeval test has open many doors to many of my clients and patients that are looking for answers. I can give you countless cases where Dr’s did not have a clue where to turn to next. These innovative testing opening doors or just confirmed my suspicions. Even once the susipcions were confirmed we did further testing to evaluate the cause of the imbalances through further analysis. By time people have come to DR M or myself they have been on the average of 20-30 dr and are just looking for answers. Dr M is to be one of the first dr’s to bring to light the importance of nutrition unlike most. My moto is “give the nutrients the body is lacking and then it can have ability to repair itself.” I go one step further and to find out why you are lacking these nutrients. This is what seperates me from the rest of health professionals. Dr M is unique in how he intergrats what I call PNEI (psychoneuroendoimmunology). PNEI is the foundations of where all pathology of majority of diseases orginate from. I am for one will be the first in line waiting for his book to come out because it will be an incredible resource tool for me in the future. Since getting into the immune system through cytokins testing there are alot of doors that are going to open up and I will better be able to put the icing on many of cases that endos have no soluition for. The secret to your getting better is to look at the intergration of PNEI other wise you are missing >60% of the puzzle. This is why people only get better never well

    I have used DR M approach a number of times and what he saids is the truth. It has also resulted in less testosteone replacement given to younger guys. Majority of our guys under 25 avoid TRT through looking at the cause vs the effect. I am huge on nutrition and identifying these imbalances because many guys through proper nutritonal evaluations where able to get restarted again naturally.

    Your constipation is most likely coming from celiac or gluten senstivity. To confirm it stop eating gluten for 6 months then tell me how your symptoms improve. I suspected some one with gluten sensitivity and had him stop eating it. His symptoms resolved. I sent him to a GI to get endoscopy down. GI dr said nothing wrong eat what you want. The next morning he had a piece of toast and nearly crapped him self. Again this is some of the wonderful advice dr’s give and then had the professional courtesy to call me “quack”. After stop eating gluten for 4 months we re ran his adrenal saliva it was all back to normal and also his antibodies returned to normal in thyroid.

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