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I currently take 400mg of 5-HTP daily and L-Tyroisine on occasion. I was considering adding SAM-E but have heard it can make anxiety worse.
Anyone with expierience with SAM-E?
I used Sam-e for a long time at 400mg/day and never experienced any anxiety from it. I used it as an antidepressant and it worked great. I don’t use it anymore as I don’t have problems with depression anymore due to balancing my hormones.
@jasonshadow 2273 wrote:
I currently take 400mg of 5-HTP daily and L-Tyroisine on occasion. I was considering adding SAM-E but have heard it can make anxiety worse.
Anyone with expierience with SAM-E?
What are you intending to use it for?
@MetalMX 2283 wrote:
What are you intending to use it for?
undermethalation and depression
Can you take 5-HTP with SAM-E?
@jasonshadow 2287 wrote:
undermethalation and depression
Can you take 5-HTP with SAM-E?
I wouldn’t both increase serotonin and their are reports of serotonin syndrome if two such supplements are combined.
Go with one or the other. P5P might increase serotonin better than SAMe and 5-HTP, although i am only basing this on how i felt when i tried each of these supplements. I had no depression and terrific moods on P5P all the time.
Tryptophan converts into 5-Hydroxytryptophan which converts into Serotonin this then also goes to create Melatonin.
5HTP to serotonin conversion requires P5P (The Active form of B6). P5P is also necessary to produce the neurotransmitters GABA, dopamine, norepinephrine, epinephrine as well as the hemoglobin in red blood cells.
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