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Dr. Mariano, I recall you commenting on the fact that the adrenals don’t usually hurt when there is adrenal dysfunction/ low cortisol, and that this achiness could be the kidneys, as they are encapsulated and when inflamed could cause pain. I experience what I have always thought was adrenal pain- this happens when I stimulate my thyroid- whether it be from exogenous thyroid hormone, or a supplement that allows my thyroid to work better (or my body to absorb thyroid hormone better). This achiness is centered around my waist in the back. It is sometimes a tightness, like a band and sometimes just aching. It is sometimes accompanied by a weak feeling in my arms and legs and anxiety. It is relieved by adrenal cortex extract or isocort. It most often happens at night. This seems to be my adrenals trying to squeeze out cortisol. My question is, do you think this is dangerous?
I have brought my ferritin up to 96- I was also wondering how long it takes for adequate ferritin to positively affect the adrenals? I am tolerating some increased iodine, B12 and vitamin D, but still cannot tolerate much in the way of thyroid hormone- in fact, I have pretty much given up trying to take any.Thank you, Chris
@misseschris 1336 wrote:
Dr. Mariano, I recall you commenting on the fact that the adrenals don’t usually hurt when there is adrenal dysfunction/ low cortisol, and that this achiness could be the kidneys, as they are encapsulated and when inflamed could cause pain. I experience what I have always thought was adrenal pain- this happens when I stimulate my thyroid- whether it be from exogenous thyroid hormone, or a supplement that allows my thyroid to work better (or my body to absorb thyroid hormone better). This achiness is centered around my waist in the back. It is sometimes a tightness, like a band and sometimes just aching. It is sometimes accompanied by a weak feeling in my arms and legs and anxiety. It is relieved by adrenal cortex extract or isocort. It most often happens at night. This seems to be my adrenals trying to squeeze out cortisol. My question is, do you think this is dangerous?
I have brought my ferritin up to 96- I was also wondering how long it takes for adequate ferritin to positively affect the adrenals? I am tolerating some increased iodine, B12 and vitamin D, but still cannot tolerate much in the way of thyroid hormone- in fact, I have pretty much given up trying to take any.Thank you, Chris
The adrenals are above the kidneys. The kidneys are covered by the ribs, and thus are high above the waist or lower spine.
Excessive pro-inflammatory signaling (and the resultant immune system overactivity) may be a cause of low cortisol output from the adrenal glands (cortisol production needs to be lowered to allow an increase in immune system pro-inflammatory activity).
The increase in pro-inflammatory signal mediated actions may lead to various pain conditions (including back pain, arthritis, fibromyalgia, migraine, etc.) and the loss of energy (e.g. sensation of weakness). Increasing Cortisol, via supplementation, may reverse some of the pro-inflammatory activities.
It is important to look for other causes contributing to pro-inflammatory signaling, since Cortisol is often not sufficient to address all the causes of increase pro-inflammatory signaling (e.g. excessive sympathetic nervous system activity, hypothyroidism, metabolic-nutritional deficiencies, etc.).
Adequate iron affects adrenal function fairly rapidly. If no improvement occurs, then there are other causes of low adrenal output which exist that are not being addressed adequately. Thus the search continues.
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