B vitamins relieve neuropathic pain behaviors induced by infraorbital nerve constriction in rats Life Sci. 2012 Aug 24; Kopruszinski CM, Reis RC, Chichorro JG Abstract AIMS: There is mounting evidence that use of B vitamins can help control neuropathic pain. This study investigated if treatment with B1, B6 and B12 vitamins, alone or in combination …
Obesity in Bipolar Disorder: An Overview Curr Psychiatry Rep. 2012 Aug 18; McElroy SL, Keck PE Abstract Bipolar disorder (BD) is associated with obesity, overweight, and abdominal obesity, and BD individuals with obesity have a greater illness burden. Factors related to BD, its treatment, and the individual may all contribute to BD’s association with obesity. …
Quetiapine, an Atypical Antipsychotic, Is Protective against Autoimmune-Mediated Demyelination by Inhibiting Effector T Cell Proliferation Feng Mei, Sheng Guo, Yangtao He, Linyun Wang, Hongkai Wang, Jianqin Niu, Jiming Kong, Xinmin Li, Yuzhang Wu, Lan Xiao PLoS One. 2012;7(8):e42746. Epub 2012 Aug 13. Abstract Quetiapine (Que), a commonly used atypical antipsychotic drug (APD), can prevent myelin …
Seroquel Reduces Autoimmune-Mediated Demyelination and IL-2 Read More »
Mental fatigue caused by prolonged cognitive load associated with sympathetic hyperactivity Behav Brain Funct. 2011;7:17 Mizuno K, Tanaka M, Yamaguti K, Kajimoto O, Kuratsune H, Watanabe Y Abstract BACKGROUND: It is known that chronic fatigue is associated with sympathetic hyperactivity. However, the relationship between autonomic function and mental fatigue caused by a prolonged mental load …
Mental Fatigue Associated with Sympathetic Hyperactivity Read More »
The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men J Clin Endocrinol Metab. 2004 Jul;89(7):3313-8 Malkin CJ, Pugh PJ, Jones RD, Kapoor D, Channer KS, Jones TH. Abstract Testosterone has immune-modulating properties, and current in vitro evidence suggests that testosterone may suppress the expression of the proinflammatory cytokines TNF-alpha, …
Stress, food, and inflammation: psychoneuroimmunology and nutrition at the cutting edge Psychosom Med. 2010 May;72(4):365-9 Kiecolt-Glaser JK Abstract Inflammation is the common link among the leading causes of death. Mechanistic studies have shown how various dietary components can modulate key pathways to inflammation, including sympathetic activity, oxidative stress, transcription factor nuclear factor-kappaB activation, and …
Schizophrenia genes, epigenetics and psychoneuroimmunology therapeutics: all make sense now? J Psychopharmacol. 2011 Jun;25(6):713-4 Müller N, Dursun SM Abstract Genetics, epigenetics, infection as an environmental factor, functional findings for the immune system, and a therapeutic approach with anti-inflammatory therapy provide evidence for a pivotal role of the immune system in schizophrenia. This field, therefore, should …
Seizure-induced brain-borne inflammation sustains seizure recurrence and blood-brain barrier damage Ann Neurol. 2012 Jul;72(1):82-90 Librizzi L, Noè F, Vezzani A, de Curtis M, Ravizza T Abstract OBJECTIVE: Epilepsy is a common neurological disorder characterized by recurrent seizures often unresponsive to pharmacological treatment. Brain inflammation is considered a crucial etiopathogenetic mechanism of epilepsy that could be …
Psychoneuroimmunologic factors in inflammatory bowel disease Inflamm Bowel Dis. 2011 Mar;17(3):849-57 Authors: Mackner LM, Clough-Paabo E, Pajer K, Lourie A, Crandall WV Abstract BACKGROUND: Bidirectional relationships between the immune system, nervous system, and psychological processes likely exist in inflammatory bowel disease (IBD) because stress can affect IBD, and IBD is associated with an increased risk …
Psychoneuroimmunologic Factors In Inflammatory Bowel Disease Read More »
Dietary intakes of berries and flavonoids in relation to cognitive decline Ann Neurol. 2012 Jul;72(1):135-43 Authors: Devore EE, Kang JH, Breteler MM, Grodstein F Abstract OBJECTIVE: Berries are high in flavonoids, especially anthocyanidins, and improve cognition in experimental studies. We prospectively evaluated whether greater long-term intakes of berries and flavonoids are associated with slower rates …
Berries and flavonoids reduce cognitive decline. Read More »