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Chronic Microglial Activation After an Inflammatory Event

Systemic lipopolysaccharide (LPS)-induced microglial activation results in different temporal reduction of CD200 and CD200 receptor gene expression in the brain. Related Articles Systemic lipopolysaccharide (LPS)-induced microglial activation results in different temporal reduction of CD200 and CD200 receptor gene expression in the brain. J Neuroimmunol. 2009 Sep 29;214(1-2):78-82 Authors: Masocha W LPS activates microglia, which are …

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Smoking Cessation Pharmacotherapy Does Not Work Well

Comparative Effectiveness of 5 Smoking Cessation Pharmacotherapies in Primary Care Clinics [Original Investigation] Stevens S. Smith, PhD; Danielle E. McCarthy, PhD; Sandra J. Japuntich, PhD; Bruce Christiansen, PhD; Megan E. Piper, PhD; Douglas E. Jorenby, PhD; David L. Fraser, MS; Michael C. Fiore, MD, MPH; Timothy B. Baker, PhD; Thomas C. Jackson, MD Arch Intern …

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Physical Activity Improves Male Colorectal Cancer Survival

Physical Activity and Male Colorectal Cancer Survival [Original Investigation] Jeffrey A. Meyerhardt, MD, MPH; Edward L. Giovannucci, MD, ScD; Shuji Ogino, MD, PhD; Gregory J. Kirkner; Andrew T. Chan, MD, MPH; Walter Willett, MD, DrPH; Charles S. Fuchs, MD, MPH Arch Intern Med. 2009;169(22):2102-2108. Background Although physically active individuals have a lower risk of developing …

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Physical Activity Reduces Decline in Kidney Function Among Older Adults

Physical Activity and Rapid Decline in Kidney Function Among Older Adults [Original Investigation] Cassianne Robinson-Cohen, MS; Ronit Katz, DPhil; Dariush Mozaffarian, MD, DrPH; Lorien S. Dalrymple, MD, MPH; Ian de Boer, MD, MS; Mark Sarnak, MD, MS; Mike Shlipak, MD, MPH; David Siscovick, MD, MPH; Bryan Kestenbaum, MD, MS Arch Intern Med. 2009;169(22):2116-2123. Background Habitual …

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Coffee, Decaffeinated Coffee, and Tea Consumption associated with reduced Type 2 Diabetes Mellitus.

Coffee, Decaffeinated Coffee, and Tea Consumption in Relation to Incident Type 2 Diabetes Mellitus: A Systematic Review With Meta-analysis [Review Article] Rachel Huxley, DPhil; Crystal Man Ying Lee, PhD; Federica Barzi, PhD; Leif Timmermeister; Sebastien Czernichow, MD, PhD; Vlado Perkovic, MD, PhD; Diederick E. Grobbee, MD, PhD; David Batty, PhD; Mark Woodward, PhD Arch Intern …

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Children who will grow up to develop adult schizophrenia struggle with verbal reasoning and lag in working memory, attention, and processing speed: A 30-Year Study.

Static and Dynamic Cognitive Deficits in Childhood Preceding Adult Schizophrenia: A 30-Year Study. Am J Psychiatry. 2010 Jan 4; Authors: Reichenberg A, Caspi A, Harrington H, Houts R, Keefe RS, Murray RM, Poulton R, Moffitt TE OBJECTIVE: Premorbid cognitive deficits in schizophrenia are well documented and have been interpreted as supporting a neurodevelopmental etiological model. …

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Abuse in childhood linked to migraine and other pain disorders

(Via EurekAlert! – Breaking News.) Abuse in childhood linked to migraine and other pain disorders: “Researchers from the American Headache Society’s Women’s Issues Section Research Consortium found that incidence of childhood maltreatment, especially emotional abuse and neglect, are prevalent in migraine patients. Full findings of the study appear in the January issue of Headache: The …

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Caffeine Linked to Reduced Liver Fibrosis (CME/CE)

Caffeine Linked to Reduced Liver Fibrosis: “Caffeine may help reduce hepatic fibrosis in patients with chronic liver disease, a cross-sectional study showed.” Increased caffeine consumption is associated with reduced hepatic fibrosis HEPATOLOGY 2010;51:201-209. Apurva A. Modi 1, Jordan J. Feld 1 2, Yoon Park 1, David E. Kleiner 3, James E. Everhart 4, T. Jake …

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Leptin via Leptin-Linked Gene Reverses Diabetes

Leptin-Linked Gene Reverses Diabetes in Mice (CME/CE): “The hunger hormone leptin can reverse diabetes (MedPage Today) — at least in mice — without causing weight loss, researchers have discovered.” Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene Cell Metabolism, Volume 11, Issue 1, 11-22, 6 January 2010 Kristina Hedbacker1, Kıvanç Birsoy1, Robert W. Wysocki1, 2, Esra …

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Metabolic Tests Ignored in Medicaid Patients on Antipsychotics

Metabolic Tests Ignored in Medicaid Patients on Antipsychotics (CME/CE): “Antipsychotic-induced metabolic disturbances receive little attention among Medicaid patients treated with second-generation antipsychotics, according to an analysis of more than 100,000 cases.” Antipsychotic-induced metabolic disturbances receive little attention among Medicaid patients treated with second-generation drugs, according to an analysis of more than 100,000 cases. Slightly more …

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