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Resveratrol vs. Brushing and Flossing

Effect of resveratrol and modulation of cytokine production on human periodontal ligament cells Cytokine. 2012 Jun 28; Authors: Rizzo A, Bevilacqua N, Guida L, Annunziata M, Romano Carratelli C, Paolillo R Abstract   Periodontitis is a multifactorial polymicrobial infection characterized by a destructive inflammatory process. Porphyromonas gingivalis, a Gram-negative anaerobic black-pigmented rod, which produces several …

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Flaxseed oil reduces adipocyte size, adipose monocyte chemoattractant protein-1 levels and T-cell infiltration

Dietary flaxseed oil reduces adipocyte size, adipose monocyte chemoattractant protein-1 levels and T-cell infiltration in obese, insulin-resistant rats Cytokine. 2012 Aug;59(2):382-91 Authors: Baranowski M, Enns J, Blewett H, Yakandawala U, Zahradka P, Taylor CG Abstract BACKGROUND: Adipocyte dysfunction is characterized by an increase in adipocyte size and changes to their adipokine profiles. Immune cell infiltration …

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Effect of vitamin D(3) on chemokine expression in pulmonary tuberculosis.

Effect of vitamin D(3) on chemokine expression in pulmonary tuberculosis Cytokine. 2012 Jul 14; Authors: Selvaraj P, Harishankar M, Singh B, Banurekha VV, Jawahar MS Abstract 1,25 Dihydroxy vitamin D(3) (vitamin D(3)) is an immunomodulator and its deficiency has been associated with susceptibility to tuberculosis. We have studied the immunoregulatory role of vitamin D(3) on …

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Non-alcoholic fatty liver disease is a pro-inflammatory condition

Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease Cytokine. 2012 Aug;59(2):442-9 Authors: Coulon S, Francque S, Colle I, Verrijken A, Blomme B, Heindryckx F, De Munter S, Prawitt J, Caron S, Staels B, Van Vlierberghe H, Van Gaal L, Geerts A Abstract The liver is a major target of injury …

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Does this mean Viagra can treat depression?

Sildenafil (Viagra®) down regulates cytokines and prevents demyelination in a cuprizone-induced MS mouse model Cytokine. 2012 Jun 30; Authors: Nunes AK, Rapôso C, Luna RL, Cruz-Höfling MA, Peixoto CA Abstract Sildenafil induces cGMP accumulation through phosphodiesterase-5 (PDE5) inhibition.  cGMP-pathways protect oligodendrocytes and modulate astroglial and microglial reactions. Microglia and astrocytes play an important role in …

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Substitute Autism for this finding: Poor nutrition at age 3 is associated with schizotypal personality at age 23

Poor nutrition at age 3 and schizotypal personality at age 23: the mediating role of age 11 cognitive functioning.   Am J Psychiatry. 2012 Aug 1;169(8):822-30 Authors: Venables PH, Raine A Abstract OBJECTIVE: Poor prenatal nutrition has been associated with schizophrenia spectrum disorders in the Netherlands and China, and it has been suggested that perinatal and postnatal …

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N-acetylcysteine reduces Cannabis Dependence

A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents.   Am J Psychiatry. 2012 Aug 1;169(8):805-12 Authors: Gray KM, Carpenter MJ, Baker NL, Desantis SM, Kryway E, Hartwell KJ, McRae-Clark AL, Brady KT Abstract OBJECTIVE: Preclinical findings suggest that the over-the-counter supplement N-acetylcysteine (NAC), via glutamate modulation in the nucleus accumbens, holds promise as …

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Metformin reduces antipsychotic-induced amenorrhea and weight gain in women with schizophrenia

Metformin for treatment of antipsychotic-induced amenorrhea and weight gain in women with first-episode schizophrenia: a double-blind, randomized, placebo-controlled study   Am J Psychiatry. 2012 Aug 1;169(8):813-21 Authors: Wu RR, Jin H, Gao K, Twamley EW, Ou JJ, Shao P, Wang J, Guo XF, Davis JM, Chan PK, Zhao JP Abstract OBJECTIVE: Data on the treatment …

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DHEA and DHEA-S increase in response to acute psychosocial stress

DHEA and DHEA-S response to acute psychosocial stress in healthy men and women Biol Psychol. 2012 May;90(2):143-9DHEA and DHEA-S response to acute psychosocial stress in healthy men and women. Authors: Lennartsson AK, Kushnir MM, Bergquist J, Jonsdottir IH Abstract This study investigates the effect of acute psychosocial stress on serum concentrations of DHEA and DHEA-S …

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Glucocorticoids Protect Against Effects of Stress on the Amygdala

Glucocorticoids Protect Against the Delayed Behavioral and Cellular Effects of Acute Stress on the Amygdala. Biol Psychiatry. 2012 May 7; Authors: Rao RP, Anilkumar S, McEwen BS, Chattarji S Abstract BACKGROUND: A single episode of acute immobilization stress has previously been shown to trigger a delayed onset of anxiety-like behavior and spinogenesis in the basolateral …

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