Blueberry Juice May Boost Memory (Via WebMD Health.) ———- Blueberry Supplementation Improves Memory in Older Adults J Agric Food Chem. 2010 Jan 4. [Epub ahead of print] Krikorian R, Shidler MD, Nash TA, Kalt W, Vinqvist-Tymchuk MR, Shukitt-Hale B, Joseph JA. The prevalence of dementia is increasing with expansion of the older adult population. In …
Reduced capacity to sustain positive emotion in major depression reflects diminished maintenance of fronto-striatal brain activation.: “ Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22445-50 Authors: Heller AS, Johnstone T, Shackman AJ, Light SN, Peterson MJ, Kolden GG, Kalin NH, Davidson RJ Anhedonia, the loss of pleasure or interest in previously rewarding stimuli, …
Brain Scan Offers First Biological Test in Diagnosis of Post-Traumatic Stress Disorder Scientific American – Psychiatry 1/22/10 Carina Storrs The synchronous neural interactions test as a functional neuromarker for post-traumatic stress disorder (PTSD): a robust classification method based on the bootstrap. J Neural Eng. 2010 Feb;7(1):16011. Epub 2010 Jan 20. Georgopoulos AP, Tan HR, Lewis …
The anxiolytic effect of environmental enrichment is mediated via amygdalar CRF receptor type 1. Mol Psychiatry. 2010 Jan 19; Authors: Sztainberg Y, Kuperman Y, Tsoory M, Lebow M, Chen A Environmental enrichment (EE) is known to have an anxiolytic effect in several animal models; however, the molecular mechanisms underlying these behavioral changes are not understood. …
Reduction in CRF Receptor type 1 expression in the Amygdala reduces Anxiety Read More »
CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):912-7 Authors: Huising MO, van der Meulen T, Vaughan JM, Matsumoto M, Donaldson CJ, Park H, Billestrup N, Vale WW Corticotropin-releasing factor (CRF), originally characterized as the …
CRF stimulates Pancreatic Beta Cell Insulin Secretion and Beta Cell Proliferation Read More »
Levetiracetam inhibits interleukin-1beta inflammatory responses in the hippocampus and piriform cortex of epileptic rats. Neurosci Lett. 2010 Jan 14; Authors: Kim JE, Choi HC, Song HK, Jo SM, Kim DS, Choi SY, Kim YI, Kang TC Levetiracetam (LEV, 2S-(oxo-1-pyrrolidinyl)butanamide, Keppra(R), UCB Pharma) is a new antiepileptic drug used to treat certain types of seizures in …
The BDNF Val66Met polymorphism affects HPA-axis reactivity to acute stress. Psychoneuroendocrinology. 2010 Jan 13; Authors: Alexander N, Osinsky R, Schmitz A, Mueller E, Kuepper Y, Hennig J BACKGROUND: Growing evidence suggests that individual differences in HPA-axis reactivity to psychosocial stress are partly due to heritable influences. However, knowledge about the role of specific genetic variants …
BDNF variant from Val66Met polymorphism reduces HPA-axis reactivity to acute stress. Read More »
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1 Nature Genetics Published online: 17 January 2010 | doi:10.1038/ng.523 Francis J McMahon1, Nirmala Akula1, Thomas G Schulze1,2, Pierandrea Muglia3,4, Federica Tozzi3, Sevilla D Detera-Wadleigh1, C J M Steele1, René Breuer2, Jana Strohmaier2, Jens R Wendland1, Manuel Mattheisen5,6,7, Thomas W Mühleisen5,6, …
The major mood disorders have significant genetic overlap Read More »
Effects of methylprednisolone and glatiramer acetate on nitric oxide formation of cytokine-stimulated cells from the rat oligodendroglial cell line OLN-93. Neuroimmunomodulation. 2010;17(1):23-30 Authors: Holzknecht C, Röhl C OBJECTIVES: In multiple sclerosis, an autoimmune inflammatory disease, oligodendroglia are primarily affected and play an important role in the onset and process of the degeneration of neuronal axons. …
Kainic acid-activated microglia mediate increased excitability of rat hippocampal neurons in vitro and in vivo: crucial role of interleukin-1beta. Neuroimmunomodulation. 2010;17(1):31-8 Authors: Zheng H, Zhu W, Zhao H, Wang X, Wang W, Li Z OBJECTIVE: It is known that highly activated microglia and the consequent production of inflammatory cytokines were associated with neuroexcitotoxic injuries. The …