Author name: Romeo Mariano, M.D.

A heartfelt response: Oxytocin effects on response to social stress in men and women   Biol Psychol. 2012 Apr;90(1):1-9 Authors: Kubzansky LD, Mendes WB, Appleton AA, Block J, Adler GK Abstract BACKGROUND: Animal research indicates that oxytocin is involved in social behavior, stress regulation, and positive physiologic adaptation. This study examines whether oxytocin enhances adaptive …

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Selenium and prostate cancer: systematic review and meta-analysis   Am J Clin Nutr. 2012 Jul;96(1):111-22 Authors: Hurst R, Hooper L, Norat T, Lau R, Aune D, Greenwood DC, Vieira R, Collings R, Harvey LJ, Sterne JA, Beynon R, Savovic J, Fairweather-Tait SJ Abstract BACKGROUND: Prostate cancer is a growing public health problem. Several human studies …

Selenium and prostate cancer Read More »

Maternal antibodies to dietary antigens and risk for nonaffective psychosis in offspring   Am J Psychiatry. 2012 Jun;169(6):625-32 Authors: Karlsson H, Blomström Å, Wicks S, Yang S, Yolken RH, Dalman C Abstract OBJECTIVE:The authors analyzed archival dried blood spots obtained from newborns to assess whether levels of immunoglobulin G (IgG) directed at dietary antigens were …

Maternal Gluten Sensitivity Raises Risk for Psychosis in Children Read More »

When grief makes you sick: Bereavement induced systemic inflammation is a question of genotype Authors: Schultze-Florey CR, Martínez-Maza O, Magpantay L, Breen EC, Irwin MR, Gündel H, O’Connor MFBrain Behav Immun. 2012 Jun 23; Abstract Although bereavement is associated with increased morbidity and mortality in the surviving spouse, some widow(er)s remain healthy. Genetic variability in expression …

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The Nature of Dopamine Dysfunction in Schizophrenia and What This Means for Treatment: Meta-analysis of Imaging Studies   Arch Gen Psychiatry. 2012 Apr 2; Authors: Howes OD, Kambeitz J, Kim E, Stahl D, Slifstein M, Abi-Dargham A, Kapur S Abstract CONTEXT: Current drug treatments for schizophrenia are inadequate for many patients, and despite 5 decades …

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Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge.   Biol Psychiatry. 2012 Jun 13; Authors: Neufeld-Cohen A, Kelly PA, Paul ED, Carter RN, Skinner E, Olverman HJ, Vaughan JM, Issler O, Kuperman Y, Lowry CA, Vale WW, Seckl …

Type 2 Corticotropin-Releasing Factor Receptor Stimulation Increases Anxiety Read More »

Simple Viewing Tests Can Detect Eye Movement Abnormalities That Distinguish Schizophrenia Cases from Controls with Exceptional Accuracy.   Biol Psychiatry. 2012 May 22; Authors: Benson PJ, Beedie SA, Shephard E, Giegling I, Rujescu D, St Clair D Abstract BACKGROUND: We have investigated which eye-movement tests alone and combined can best discriminate schizophrenia cases from control …

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Why do some depressed outpatients who are in remission according to the Hamilton Depression Rating Scale not consider themselves to be in remission? J Clin Psychiatry. 2012 Jun;73(6):790-5 Authors: Zimmerman M, Martinez JA, Attiullah N, Friedman M, Toba C, Boerescu DA, Rahgeb M Abstract OBJECTIVE: In treatment studies of depression, remission is typically defined narrowly, based …

Because They Are Still Ill… Read More »

Arterial Stiffness and Vitamin D Levels: the Baltimore Longitudinal Study of Aging J Clin Endocrinol Metab. 2012 Jul 5; Authors: Giallauria F, Milaneschi Y, Tanaka T, Maggio M, Canepa M, Elango P, Vigorito C, Lakatta EG, Ferrucci L, Strait J Abstract Context: The importance of vitamin D for bone health has long been acknowledged. Recent evidence …

Vitamin D Reduces Arterial Stiffness Read More »

Sitagliptin Exerts an Antinflammatory Action J Clin Endocrinol Metab. 2012 Jun 28; Authors: Makdissi A, Ghanim H, Vora M, Green K, Abuaysheh S, Chaudhuri A, Dhindsa S, Dandona P Abstract Context:  Sitagliptin is an inhibitor of the enzyme dipeptidyl peptidase-IV (DPP-IV), which degrades the incretins, glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide, and thus, sitagliptin increases …

Sitagliptin (Januvia) has antiinflammatory effects Read More »