Author name: Romeo Mariano, M.D.

Antidepressant combination for major depression in incomplete responders-a systematic review. J Affect Disord. 2012 Jul 24; Authors: Lopes Rocha F, Fuzikawa C, Riera R, Ramos MG, Hara C Abstract BACKGROUND: Antidepressant combination has been suggested as a strategy to increase treatment efficacy. The objective of this study was to perform a systematic review and meta-analysis …

Antidepressant Combination for Major Depression: Flaws in Evidenced-Based Medicine Read More »

Risk of future depression in people who are obese but metabolically healthy: the English longitudinal study of ageing Molecular Psychiatry 17, 940 (September 2012). doi:10.1038/mp.2012.30 M Hamer, G D Batty & M Kivimaki Abstract There is some evidence to suggest that obesity is a risk factor for the development of depression, although this is not …

Obesity Increases the Risk for Depression Particularly if Not Metabolically Healthy Read More »

Mood-state effects on amygdala volume in bipolar disorder J Affect Disord. 2012 Aug;139(3):298-301 Authors: Foland-Ross LC, Brooks JO, Mintz J, Bartzokis G, Townsend J, Thompson PM, Altshuler LL Abstract BACKGROUND: Prior structural neuroimaging studies of the amygdala in patients with bipolar disorder have reported higher or lower volumes, or no difference relative to healthy controls. …

Amygdala is smaller in bipolar disorder depressed patients Read More »

Astrocytes are seen signaling through gap junctions using calcium waves in this video from garlandscien.

Pediatric bipolar disorder and ADHD: Family history comparison in the LAMS clinical sample J Affect Disord. 2012 Mar 30; Authors: Arnold LE, Mount K, Frazier T, Demeter C, Youngstrom EA, Fristad MA, Birmaher B, Horwitz S, Findling RL, Kowatch R, Axelson D Abstract   BACKGROUND: Transgenerational association of bipolar spectrum disorder (BPSD) and attention deficit/hyperactivity …

Children with ADHD and Anger have a Mood Disorder Too Read More »

The effects of psychotherapy for adult depression on suicidality and hopelessness: A systematic review and meta-analysis J Affect Disord. 2012 Jul 23; Authors: Cuijpers P, de Beurs DP, van Spijker BA, Berking M, Andersson G, Kerkhof AJ Abstract BACKGROUND: Although treatment guidelines suggest that suicidal patients with depression should be treated for depression with psychotherapy, …

The Problem of Meta-Analysis of Psychotherapy's Effect on Suicidality Read More »

Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: Randomized double-blind placebo-controlled study J Affect Disord. 2012 Apr 18; Authors: Abbasi SH, Hosseini F, Modabbernia A, Ashrafi M, Akhondzadeh S Abstract BACKGROUND: It has been proposed that the mechanism of the antidepressant effect of celecoxib is linked …

Celebrex is a Potent Antidepressant Read More »

Influence of Omega-3 Fatty Acid Status on the Way Rats Adapt to Chronic Restraint Stress PLoS One. 2012;7(7):e42142. Epub 2012 Jul 30. Hennebelle M, Balasse L, Latour A, Champeil-Potokar G, Denis S, Lavialle M, Gisquet-Verrier P, Denis I, Vancassel S. Abstract Omega-3 fatty acids are important for several neuronal and cognitive functions. Altered omega-3 fatty …

Omega-3 Fatty Acids Improve Capacity to Adapt to Stress Read More »

A Prospective Study of Weight Training and Risk of Type 2 Diabetes Mellitus in Men Arch Intern Med. 2012 Aug 6;:1-7 Authors: Grøntved A, Rimm EB, Willett WC, Andersen LB, Hu FB Abstract BACKGROUND The role of weight training in the primary prevention of type 2 diabetes mellitus (T2DM) is largely unknown. METHODS To examine …

150 Minutes a Week of Weight Training plus Aerobic Exercise Reduces Risk of Diabetes Read More »

Residual memory dysfunction in recurrent major depressive disorder-A longitudinal study from Juntendo University Mood Disorder Project J Affect Disord. 2012 Jul 23; Authors: Maeshima H, Baba H, Nakano Y, Satomura E, Namekawa Y, Takebayashi N, Suzuki T, Mimura M, Arai H Abstract BACKGROUND: Depression may increase the risk of developing Alzheimer’s disease. Large cohort studies …

Residual Memory Dysfunction In Major Depressive Disorder Means Incomplete Treatment Read More »