Effects of n-3 fatty acids on macro- and microvascular function in subjects with type 2 diabetes mellitus. Am J Clin Nutr. 2010 Jan 13; Authors: Stirban A, Nandrean S, Götting C, Tamler R, Pop A, Negrean M, Gawlowski T, Stratmann B, Tschoepe D BACKGROUND: Recent evidence supports the protective effects of n-3 (omega-3) fatty acids …
Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice. Ann Neurol. 2009 Oct;66(4):564-8 Authors: Eikermann-Haerter K, Baum MJ, Ferrari MD, van den Maagdenberg AM, Moskowitz MA, Ayata C Familial hemiplegic migraine type 1 (FHM1), a severe migraine with aura variant, is caused by mutations in the CACNA1A gene. Mutant mice carrying …
Role of endogenous testosterone concentration in pediatric stroke. Ann Neurol. 2009 Dec;66(6):754-8 Authors: Normann S, de Veber G, Fobker M, Langer C, Kenet G, Bernard TJ, Fiedler B, Sträter R, Goldenberg NA, Nowak-Göttl U Previous studies have indicated a male predominance in pediatric stroke. To elucidate this gender disparity, total testosterone concentration was measured in …
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Stimulation of the subthalamic nucleus and impulsivity: release your horses. Ann Neurol. 2009 Dec;66(6):817-24 Authors: Ballanger B, van Eimeren T, Moro E, Lozano AM, Hamani C, Boulinguez P, Pellecchia G, Houle S, Poon YY, Lang AE, Strafella AP OBJECTIVE: In Parkinson disease (PD) patients, deep brain stimulation (DBS) of the subthalamic nucleus (STN) may contribute …
Endocrine consequences of opioid therapy. Psychoneuroendocrinology. 2009 Dec;34 Suppl 1:S162-8 Authors: Aloisi AM, Aurilio C, Bachiocco V, Biasi G, Fiorenzani P, Pace MC, Paci V, Pari G, Passavanti G, Ravaioli L, Sindaco G, Vellucci R, Ceccarelli I Gonadal hormones are known to be affected by morphine and other opioids. In this paper, we summarize data …
Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study.: “ Related Articles Arch Gen Psychiatry. 2009 Jun;66(6):617-26 Authors: Vreeburg SA, Hoogendijk WJ, van Pelt J, Derijk RH, Verhagen JC, van Dyck R, Smit JH, Zitman FG, Penninx BW CONTEXT: There is a central belief that depression is associated with hyperactivity of …
N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study. Related Articles Arch Gen Psychiatry. 2009 Jul;66(7):756-63 Authors: Grant JE, Odlaug BL, Kim SW CONTEXT: Trichotillomania is characterized by repetitive hair pulling that causes noticeable hair loss. Data on the pharmacologic treatment of trichotillomania are limited to conflicting studies of serotonergic medications. …
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Biotin-responsive basal ganglia disease in ethnic Europeans with novel SLC19A3 mutations. Arch Neurol. 2010 Jan;67(1):126-30 Authors: Debs R, Depienne C, Rastetter A, Bellanger A, Degos B, Galanaud D, Keren B, Lyon-Caen O, Brice A, Sedel F OBJECTIVE: To report the first 2 European cases of biotin-responsive basal ganglia disease and novel SLC19A3 mutations. DESIGN: Case …
Muscarinic Agonists for the Treatment of Cognition in Schizophrenia Angela K. Sellin, MD, Mujeeb Shad, MD, and Carol Tamminga, MD CNS Spectr. 2008;13(11):985-996 It is widely accepted that cholinergic activity at muscarinic receptors is required to maintain cognitive functions, including learning and memory. Memory domains are especially impaired in schizophrenia, which may explain difficulties in …
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Normative variation in self-reported sleep quality and sleep debt is associated with stimulated pro-inflammatory cytokine production. Related Articles Biol Psychol. 2009 Sep;82(1):12-7 Authors: Prather AA, Marsland AL, Hall M, Neumann SA, Muldoon MF, Manuck SB Activation of innate inflammatory pathways, marked by increased production of pro-inflammatory cytokines, has been proposed as a potential mechanism linking …