Whenever one cannot raise there DHT levels no matter what they try gels,creams,injections,ect what would be the cause of this ? would there be some kind of androgen resistance at play ? me personally for years i could never get TRT to work for me even when all my other hormones,signals were optimized no matter how high my testosterone would go i would not feel a single benefit from it , my ADIOL glucuronide levels have always been extremly low which might point to some kind of androgen resistance ? because of this problem my depression can never be fixed no matter what i try , where would one look for help in the body to solve these problems ? can suboptimal DHEA signaling cause this ?