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33 yr old male 250 lbs 6′ , on trt for 9 yrs now on and off , been on this run for 8 months , 100 mg test depo per week .
main concerns are very itchy and puffy left nipple . hot flashes , flight fight feeling all the time , high anxiety , just over stimulated !!!
fisrt lab was day of shot to get lowest readings 3/21/11:
labcorp 3/21 9:15 am
glucose 101 ref – 65-99 HIGH
bun 15 ref – 6-20
creatine 1.28 ref – .76-1.27 HIGH
total test 343 ref- 249 -836
free test 7.5 ref- 8.7-25.1 LOW
dht 37 ref – 30-85
shbg 30 ref- 20-60
tsh 2.990 ref – .450 – 4.50
prolactin 5.3 ref- 4-15.2
dhea 206.7 ref- 160-449
psa .7 ref – 0-4
igf-1 122 ref- 115-307
taking igf-1lr3 for 3 weeks , guess it dont work !!!!!vit D 26.2 ref- 32-100 LOW
estradiol , sensitive 4 ref- 3-70
b12 384 ref- 211- 946
progesterone .4 ref – .2 – 1.4
total estrogens 53 ref 40-115
next labs collected on 3/24/11 2 days after shot for peak levels:
labcorp 3/24 9:26am
thyroid panel
t4 7.9 ref- 4.5-12t3 uptake 33 ref- 24-39
free thyroxine 2.6 ref- 1.2- 4.9
total test 480 ref- 249 -836
free test 14.6 ref- 8.7-25.1
dht 48 ref – 30-85
prolactin 5.9 ref- 4-15.2
estradiol , sensitive 9 ref- 3-70
progesterone .6 ref – .2 – 1.4
total estrogens 58 ref 40-115
cortisol 17 ref – 6.2-19.4
collection period – 24hrs
total volume – 2200
metanephrines , 24 urine as follows :
normetanephrine – 498 HIGH ref – 35-482
metanephrine – 196 HIGH ref – 36-190
total metanephrine 694 HIGH ref 115-695VMA – 7.5 HIGH ref < 6 catecholamine frac as follows : norepinephrine 55 ref 15-100
eprinephrine 6 ref 2-24
calc. total ( e+ne) 61 ref 26-121
dopamine 166 ref 52-480high TSH
Low Vitamin D and b12 (need to supplement the first for 10,000iu and the second with a lozenges 1000mcg a day)
Low progesterone which may indicate a low pregnelone
Signs of insulin resistance with a 101 glucoseas for the rest its clear that your medication in pumping your testosterone isn’t effective
Low Supplement D and b12 (need to complement the first for 10,000iu and the second with a lozenges 1000mcg a day) Low progesterone which may indicate a low pregnelone. Symptoms and symptoms of blood insulin level of resistance with a 101 sugar
I prefer fasting glucose to be between 93-100 so long as there is intact gluconeogenesis and minimal insulin resistance.
Testosterone cypionate at 100 mg a week should result in good trough levels of testosterone – around 650 ng/dL. If it is less, then perhaps the half-life of testosterone cypionate is short and a dose adjustment needs to be done.
Ideally, from my point of view, TSH should be below 1.0, preferrably between 0.03 to 0.5. Not everyone can tolerate this however because of excessive pro-inflammatory signaling interacting with thyroid hormone.
Anxiety, irritability, insomnia, hot flashes indicate an excess in sympathetic nervous system activity. Outside of external stresses, this may indicate a compensatory response to metabolic problems or impaired ability to produce sufficient control signals for norepinephrine. These include serotonin, dopamine, GABA, testosterone, progesterone, estradiol, etc.
Generally, growth hormone production and signaling may be impaired by multiple other signaling problems including lack of adequate thyroid hormone, testosterone, DHEA, etc. Substances that increase liver inflammation – such as a single drink of alcohol – knock out growth hormones major effects.
Nutritional optimization is important to improve metabolism and signaling. Low vitamin D and B12 occur often when people avoid animal fat and internal organs like liver in the diet. These ingredients are part of traditional diets which are highly nutritious compared to diets in the modern era.
I prefer doing a plasma fractionated catecholamine test to the urine test since it is much more easily correlated to nervous system stress levels.
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