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What is your guys take on 5htp supplementation? What about tyrosine?
Every ssri that ive been on has been very harsh…. Does 5htp get to the brain in therapeutic amounts? What rough percentage converts to serotonin before it hits the brain? What kind of issues would one get if large amounts of serotonin were seen in the body/blood stream?
And on to tyrosine…. would it be safe to combine the two? two brids one stone kinda thing?
5-Hydroxytryptophan (5-HTP) is an option to the SSRIs (Serotonin-Reuptake Inhibitors).
About 90 % is immediately converted to Serotonin in the intestines, where it is a signal in the enteric nervous system, as opposed to the central nervous system. This may result in side effects such as nausea and diarrhea. The other 10 % may get into the brain.
Here is a decent review for 5-HTP: http://www.thorne.com/media/5htp_monograph.pdf
Here is a decent review for tyrosine: http://www.thorne.com/media/TyrosineMono12-4.pdf
interesting, seems as if the dosage for tyrosie is quite high to feel much of an effect…surprised it reduces “stress”. I figured it would increase ones sensitivity to stress through an increase in stress signaling via more norepinephrine. Surley im missing something here
Thats what i thought with 5htp. I wonder if is worth the headache investing in carbidopa…… or go back a couple steps and use tryptophan but im sure the effective dosage for that is also quite high.
When it comes to prescription medications, I recommend discussing treatment with your qualified health care provider.
Tryptophan is the direct precursor to 5-HTP. Thus both would have similar effects, though 5-HTP is pricier.
Tryptophan, when it was available as a prescribed supplement in the U.S. years ago, was great in helping reduce anxiety and helping sleep. I would usually prescribe about 1000 mg a day.
Providing the precursors to Norepinephrine does not necessarily increase Norepinephrine production.
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