Home › Forums › DISCUSSION FORUMS › PSYCHIATRY, NEUROENDOCRINOLOGY, PSYCHOIMMUNOLOGY › Provigil (Modafinil) and Adrenal Fatigue
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July 14, 2009 at 12:32 pm #1158
chaos
MemberIs there any possibility that this stimulant is “easier” on the HPA axis than adderall or perhaps even caffeine?
I have occasionally used it in place of adderall and it actually works well for ADD.
How is it different? Or, how does it stimulate without being a typical stimulant?
July 14, 2009 at 8:10 pm #2684DrMariano2
Participant@chaos 781 wrote:
Is there any possibility that this stimulant is “easier” on the HPA axis than adderall or perhaps even caffeine?
I have occasionally used it in place of adderall and it actually works well for ADD.
How is it different? Or, how does it stimulate without being a typical stimulant?
Provigil (Modafinil) IS a stimulant. Studies have shown it acts as a dopamine and norepinephrine reuptake inhibitor. It increase norepinephrine and dopamine – albeit at milder levels than other stimulants.
It additionally increases hypothalamic histamine signaling. This is different from other stimulants. Histamine is also an excitatory signal in the brain, which contributes to wakesfulness as does norepinephrine. It may not be a useful signal to increase since it can potentially trigger an inflammatory cascade.
Since it is relatively mild compared to Methylphenidate or Amphetamine, it is “easier” on the HPA Axis, though has the same risks.
At about $9 a tablet, it is a very expensive medication. One can get two Viagra pills for the price of one Provigil.
July 14, 2009 at 11:06 pm #2686chaos
Member@DrMariano 787 wrote:
Provigil (Modafinil)
At about $9 a tablet, it is a very expensive medication. One can get two Viagra pills for the price of one Provigil.
And have more fun with the former and a willing partner.
Where can I trade? Just kiddin’ 😀
July 15, 2009 at 1:08 am #2685DrMariano2
ParticipantAt $9 a tablet, is it any wonder that the FDA refused to consider Provigil as a treatment to be used in children?
March 13, 2011 at 3:18 pm #2687Laura633
MemberI can recommend a reputable pharmacy (Provigil) mega-pharm.net I received the order and it was on time and the pills work great.
P.S. 5% discount coupon code: 1b3d31ab9c -
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